Indian Journal of Public Health Research & Development

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Histological Assessment of Anti-inflammatory Effectiveness of 940 Nanometer LLLT on Carrageenan Induced Arthritis in Temporomandibular Joint in Wistar Albino Rats


Affiliations
1 Department of Oral Diagnosis, College of Dentistry, University of Baghdad, Iraq
2 Alimamain Alkhazimain Medical City, Baghdad, Iraq
     

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Low level laser therapy is very promising method to treat temporomandibular joint disorders, the aim of this study was to assess the effectiveness of different energy density of 940nm diode laser, 120 Westar albino male rats (250g weight, three months old) were used in this study, divided randomly into four experimental groups; negative control group injected with saline, positive control group injected with carrageenan solution with no treatment, study group injected with carrageenan and treated with 171J/cm2 LLLT group, and study group injected with carrageenan and treated with 74J/cm2 LLLT group, animals were euthanized in day;1,3, and 7, histological slides obtained and examined under light microscope for assess acute and chronic inflammatory infiltrations. It was concluded that LLLT using 74J/cm2 energy density had a very efficient anti-inflammatory effect.

Keywords

Anti-Inflammatory, Effectiveness, Carrageenan, Arthritis.
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  • Histological Assessment of Anti-inflammatory Effectiveness of 940 Nanometer LLLT on Carrageenan Induced Arthritis in Temporomandibular Joint in Wistar Albino Rats

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Authors

Ali Imad Al-Khassaki
Department of Oral Diagnosis, College of Dentistry, University of Baghdad, Iraq
Jamal Noori Ahmed
Department of Oral Diagnosis, College of Dentistry, University of Baghdad, Iraq
Ammar Saleh Al-Allawi
Alimamain Alkhazimain Medical City, Baghdad, Iraq

Abstract


Low level laser therapy is very promising method to treat temporomandibular joint disorders, the aim of this study was to assess the effectiveness of different energy density of 940nm diode laser, 120 Westar albino male rats (250g weight, three months old) were used in this study, divided randomly into four experimental groups; negative control group injected with saline, positive control group injected with carrageenan solution with no treatment, study group injected with carrageenan and treated with 171J/cm2 LLLT group, and study group injected with carrageenan and treated with 74J/cm2 LLLT group, animals were euthanized in day;1,3, and 7, histological slides obtained and examined under light microscope for assess acute and chronic inflammatory infiltrations. It was concluded that LLLT using 74J/cm2 energy density had a very efficient anti-inflammatory effect.

Keywords


Anti-Inflammatory, Effectiveness, Carrageenan, Arthritis.



DOI: https://doi.org/10.37506/v10%2Fi12%2F2019%2Fijphrd%2F192562