Nardostachys Jatamansi DC. Potential Herb with CNS Effects

Nardostachys jatamansi is classified as hypno-sedative in Ayurveda. It is used in treatment of insomnia, hysteria and depressive illness. The pla nt abounds in sesquiterpenes predominantly; jatamansone and nardostachone. The plant has demonstrated several pharmacological activities including hepato protective, cardio protective and hypolipidemic and antifungal. The significant effe ct is on the central nervous system, as diverse pharmacological actions, ranging from sedative to nootropic have been reported. Animal and clinical research with jatamansone, the active princi ple of the plant, has justified hypno-sedative claim of Ayurveda. Th e review summarizes, phytochemical and pharmacological investigations carried out on the plant.