Asian Journal of Pharmaceutical Research and Health Care

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Predictive Value of Hypoxemia in the Diagnosis of Pneumonia in the Pediatric Population


Affiliations
1 Department of Pediatrics, Umm Al-Qura University, Mecca, Saudi Arabia, and Department of Pediatric, Dr. Soliman Fakeeh Hospital, Jeddah − 23323, Saudi Arabia
 

Pneumonia is the leading cause of morbidity and mortality in children less than 5 years of age1. According to a systematic review, hypoxaemia as detected with pulse oximetry has been observed in 13% of children with WHO-defined pneumonia requiring hospitalisation (severe and very severe classifications). This corresponds to at least 1.5 to 2.7 million annual cases of hypoxaemic pneumonia presenting to health-care facilities2. This study was aimed to identify the clinical predictive values of hypoxemia in children with radiographic evidence of Pneumonia. A retrospective cohort study was conducted at Dr. Soliman Fakeeh Hospital. The aim of the study was to seek an association between pulse oxygen saturation and radiographic pneumonia in the pediatric age group. Data was collected and analyzed in IBM SPSS Version 20. The results were significant for hypoxemia across all age groups, [x2 (1, N=755) = 10.327, p = .001]. Approximately 94% of patients with hypoxemia had pneumonia. Due to its statistical significance, evaluation of oxygen saturation for hypoxemia may be useful in the assessment of pneumonia risk among children in settings with underprivileged resources.


Keywords

Hypoxemia, Pediatrics, Pneumonia, Predictive Value.
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  • Rudan, et al. Epidemiology and Etiology of Childhood Pneumonia. Bulletin of the World Health Organization, World Health Organization. 1 May 2008. www.scielosp.org/ article/bwho/2008.v86n5/408-416B/. https://doi.org/10.2471/BLT.07.048769. PMid: 18545744, PMCid: PMC2647437.

  • Subhi R, Adamson M, Campbell H, Weber M, Smith K, Duke T. Hypoxaemia in Developing Countries Study Group. The prevalence of hypoxaemia among ill children in developing countries: A systematic review. Lancet Infect Dis. 2009; 9:219-27. https://doi.org/10.1016/S14733099(09)70071-4.

  • Florin, T. A., et al. Variation in Emergency Department Diagnostic Testing and Disposition Outcomes in Pneumonia. Pediatrics. 2013; 132(2):237-244. DOI:10.1542/peds.2013-0179. https://doi.org/10.1542/peds.2013-0179. PMid: 23878049.

  • Shah, Sonal, et al. Lack of Predictive Value of Tachypnea in the Diagnosis of Pneumonia in Children. The Pediatric Infectious Disease Journal. 2010; 29(5):406-409. doi:10.1097/inf.0b013e3181cb45a7. https://doi.org/10.1097/INF.0b013e31 81cb45a7. PMid: 20032805.

  • Kushwah, Meenakshi S., et al. Clinical Predictors of Hypoxemia in Children with WHO Classified Pneumonia. International Journal of Contemporary Pediatrics. 2018; 5(4):1176. doi:10.18203/2349-3291.ijcp20181981. https://doi.org/10.18203/23493291.ijcp20181981.

  • Lazzerini, Marzia, et al. Hypoxaemia as a Mortality Risk Factor in Acute Lower Respiratory Infections in Children in Low and Middle-Income Countries: Systematic Review and Meta-Analysis. PloS One, Public Library of Science. 15 Sept. 2015. www.ncbi.nlm.nih.gov/pmc/articles/PMC 4570717/.

  • Alwadhi, Varun, et al. Tachypnea and Other Danger Signs vs Pulse Oximetry for Prediction of Hypoxia in Severe Pneumonia/Very Severe Disease. Indian Pediatrics. 2017; 54(9):729-734. doi:10.1007/s13312-017-1163-6. https://doi.org/10.1007/s13312-017-1163-6. PMid: 28607210.

  • Rudan, et al. Epidemiology and Etiology of Childhood Pneumonia. Bulletin of the World Health Organization, World Health Organization. 1 May 2008. www.scielosp.org/article/bwho/2008.v86n5/408-416B/.

  • Aehlert, Barbara. PALS: Pediatric Advanced Life Support Study Guide. Jones & Bartlett Learning, 2018, p.7.

  • Weber M, Usen S, Palmer A et al. Predictors of hypoxemia in hospital admission with acute respiratory tract infection in a developing country. Arch Dis Child. 1997; 76:310-14. 16. Oxygen therapy. Management of the child with. PMid: 9166021, PMCid: PMC1717166. https://doi.org/10.1136/adc.76.4.310.


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  • Predictive Value of Hypoxemia in the Diagnosis of Pneumonia in the Pediatric Population

Abstract Views: 415  |  PDF Views: 171

Authors

Saleh Al Harbi
Department of Pediatrics, Umm Al-Qura University, Mecca, Saudi Arabia, and Department of Pediatric, Dr. Soliman Fakeeh Hospital, Jeddah − 23323, Saudi Arabia

Abstract


Pneumonia is the leading cause of morbidity and mortality in children less than 5 years of age1. According to a systematic review, hypoxaemia as detected with pulse oximetry has been observed in 13% of children with WHO-defined pneumonia requiring hospitalisation (severe and very severe classifications). This corresponds to at least 1.5 to 2.7 million annual cases of hypoxaemic pneumonia presenting to health-care facilities2. This study was aimed to identify the clinical predictive values of hypoxemia in children with radiographic evidence of Pneumonia. A retrospective cohort study was conducted at Dr. Soliman Fakeeh Hospital. The aim of the study was to seek an association between pulse oxygen saturation and radiographic pneumonia in the pediatric age group. Data was collected and analyzed in IBM SPSS Version 20. The results were significant for hypoxemia across all age groups, [x2 (1, N=755) = 10.327, p = .001]. Approximately 94% of patients with hypoxemia had pneumonia. Due to its statistical significance, evaluation of oxygen saturation for hypoxemia may be useful in the assessment of pneumonia risk among children in settings with underprivileged resources.


Keywords


Hypoxemia, Pediatrics, Pneumonia, Predictive Value.

References





DOI: https://doi.org/10.18311/ajprhc%2F2019%2F24293