The Asian Journal of Experimental Chemistry

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The Root Part of Costus specious Possesses in vitro Cytotoxic Potential against Human Cancer Cell Lines from Colon, Liver and Prostate Origin


Affiliations
1 Division of Biochemistry and Plant Physiology, Sher-e-Kashmir University of Agricultural Sciences and Technology of Jammu, Jammu (J&K), India
     

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The aim of this research work was to evaluate the anticancer potential of the extracts of the traditional medicinal plant i.e. Costus speciosus. The extracts of the ischolar_main part were screened for in vitro cytotoxicity by means of SRB assay on five human cancer cell lines : colon cancer cells (COLO-205, HT-29, SW-620), liver cancer cells (HEP-2) and prostate cancer cells (DU-145). The assay yielded very interesting and significant consensus from medicinal view point as all the extracts of the plant showed remarkable cytotoxic effect on each human cancer cell line in the range of 70-92%.

Keywords

Costus speciosus, Human Cancer Cells, In vitro Cytotoxicity, SRB-Assay.
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  • The Root Part of Costus specious Possesses in vitro Cytotoxic Potential against Human Cancer Cell Lines from Colon, Liver and Prostate Origin

Abstract Views: 255  |  PDF Views: 1

Authors

Vikas Sharma
Division of Biochemistry and Plant Physiology, Sher-e-Kashmir University of Agricultural Sciences and Technology of Jammu, Jammu (J&K), India
A. K. Tiku
Division of Biochemistry and Plant Physiology, Sher-e-Kashmir University of Agricultural Sciences and Technology of Jammu, Jammu (J&K), India

Abstract


The aim of this research work was to evaluate the anticancer potential of the extracts of the traditional medicinal plant i.e. Costus speciosus. The extracts of the ischolar_main part were screened for in vitro cytotoxicity by means of SRB assay on five human cancer cell lines : colon cancer cells (COLO-205, HT-29, SW-620), liver cancer cells (HEP-2) and prostate cancer cells (DU-145). The assay yielded very interesting and significant consensus from medicinal view point as all the extracts of the plant showed remarkable cytotoxic effect on each human cancer cell line in the range of 70-92%.

Keywords


Costus speciosus, Human Cancer Cells, In vitro Cytotoxicity, SRB-Assay.