OPLC- A Novel Technique

OPLC is coming of age. Its rudimentary beginnings, some 25 years ago, have lead to innovative, highperformance products. The commercialization of modern, high efficiency columns has eliminated the need for analysts to prepare their own from TLC plates, making the technique even more accessible. Optimum performance laminar chromatography (OPLC) is a pumped flow chromatography technique that combines the user-friendly interface of HPLC with the capacity of flash chromatography and the multidimensionality of thinlayer chromatography. This review will describe the basis of modern OPLC instrumentation and the separation techniques, as well as give a brief account of some recent applications in OPLC.