Asian Journal of Pharmaceutical Research

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Current Therapeutic Targets for Neuropathic Pain


Affiliations
1 Department of Pharmaceutical Chemistry, Shreeshakti Shaikshanik Sanstha, Divine College of Pharmacy, Satana, Nashik, India
2 Bharati Vidhyapeeth College of Pharmacy, Belapur, Navi Mumbai, India
3 Department of Pharmaceutics, MET’s, Institute of Pharmacy, BKC, Adgaon, Nashik – 3, India
4 Department of Pharmacology, Shreeshakti Shaikshanik Sanstha, Divine College of Pharmacy, Satana, Nashik, India
5 Department of Pharmaceutical Chemistry, MGV’s Pharmacy College, Panchvati, Nashik, India
6 Department of Pharmaceutics, Shreeshakti Shaikshanik Sanstha, Divine College of Pharmacy, Satana, Nashik, India
     

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Nociceptive ache signals the frame to capability or real tissue harm. By contrast, neuropathic ache, which ends from damage or harm to the worried system, persists lengthy in spite of everything symptoms and symptoms of the authentic damage have disappeared. This kind of maladaptive ache affords a full-size scientific problem, because it responds poorly or unpredictably to classical analgesics. There is likewise no single, uniformly well- tolerated drug this is reliably helpful. Neuropathic ache withinside the popular populace is expected to have a occurrence ranging among 3% and 17%. Most of the remedies for neuropathic ache have slight efficacy and gift aspect consequences that restriction their use; therefore, different healing strategies are wished for patients. In this article, the contemporary trendy of care treatment, the rising pharmacological strategies until date, and the preclinical research on novel promising healing alternatives could be reviewed.


Keywords

Neuropathic pain, Inflammation, Drugs acting on neuropathic pain, Cannabinoid receptor
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  • Current Therapeutic Targets for Neuropathic Pain

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Authors

Khemchand R. Surana
Department of Pharmaceutical Chemistry, Shreeshakti Shaikshanik Sanstha, Divine College of Pharmacy, Satana, Nashik, India
Abhijeet G. Parkhe
Bharati Vidhyapeeth College of Pharmacy, Belapur, Navi Mumbai, India
Eknath D. Ahire
Department of Pharmaceutics, MET’s, Institute of Pharmacy, BKC, Adgaon, Nashik – 3, India
Anuprita R. Pawar
Department of Pharmaceutical Chemistry, Shreeshakti Shaikshanik Sanstha, Divine College of Pharmacy, Satana, Nashik, India
Survarna Khairnar
Department of Pharmacology, Shreeshakti Shaikshanik Sanstha, Divine College of Pharmacy, Satana, Nashik, India
Sunil K. Mahajan
Department of Pharmaceutical Chemistry, MGV’s Pharmacy College, Panchvati, Nashik, India
Dhananjay M. Patil
Department of Pharmaceutics, Shreeshakti Shaikshanik Sanstha, Divine College of Pharmacy, Satana, Nashik, India
Deepak D. Sonawane
Department of Pharmaceutics, Shreeshakti Shaikshanik Sanstha, Divine College of Pharmacy, Satana, Nashik, India
Sanjay J. Kshirsagar
Department of Pharmaceutics, MET’s, Institute of Pharmacy, BKC, Adgaon, Nashik – 3, India

Abstract


Nociceptive ache signals the frame to capability or real tissue harm. By contrast, neuropathic ache, which ends from damage or harm to the worried system, persists lengthy in spite of everything symptoms and symptoms of the authentic damage have disappeared. This kind of maladaptive ache affords a full-size scientific problem, because it responds poorly or unpredictably to classical analgesics. There is likewise no single, uniformly well- tolerated drug this is reliably helpful. Neuropathic ache withinside the popular populace is expected to have a occurrence ranging among 3% and 17%. Most of the remedies for neuropathic ache have slight efficacy and gift aspect consequences that restriction their use; therefore, different healing strategies are wished for patients. In this article, the contemporary trendy of care treatment, the rising pharmacological strategies until date, and the preclinical research on novel promising healing alternatives could be reviewed.


Keywords


Neuropathic pain, Inflammation, Drugs acting on neuropathic pain, Cannabinoid receptor

References