Asian Journal of Pharmaceutical Research

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Particle Engineering for Customized Drug Particles and Its Applications


Affiliations
1 GES’s Satara College of Pharmacy, Degaon, Satara (M.S.) 415004, India
     

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Particle engineering is a technique that involves the customization of particles in order to get desired properties of the pharmaceutical products. The use of particle engineering is in obtaining optimum particle size and particle size distribution and getting particles of desired size. The other aspects of the particle engineering involves the morphological changes of the drug substances. The particle engineering involves improvement of physicochemical properties such as solubility, stability, improved bioavailability and formulation of novel drug delivery systems such as pulmonary drug delivery system. This article includes various techniques used for the particle engineering such as Micronization, Spray drying, high pressure homogenization, Supercritical fluid technology and freeze drying. Article also covers the different uses of particle engineering in pharmaceutical industry.


Keywords

Cocrystals, Micronization, Particle Engineering, Pulmonary Drug Delivery, Solubility, Stability
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  • Particle Engineering for Customized Drug Particles and Its Applications

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Authors

Niraj Kale
GES’s Satara College of Pharmacy, Degaon, Satara (M.S.) 415004, India
Ketaki Shinde
GES’s Satara College of Pharmacy, Degaon, Satara (M.S.) 415004, India
Sonam Bendre
GES’s Satara College of Pharmacy, Degaon, Satara (M.S.) 415004, India
Suhit Gilda
GES’s Satara College of Pharmacy, Degaon, Satara (M.S.) 415004, India

Abstract


Particle engineering is a technique that involves the customization of particles in order to get desired properties of the pharmaceutical products. The use of particle engineering is in obtaining optimum particle size and particle size distribution and getting particles of desired size. The other aspects of the particle engineering involves the morphological changes of the drug substances. The particle engineering involves improvement of physicochemical properties such as solubility, stability, improved bioavailability and formulation of novel drug delivery systems such as pulmonary drug delivery system. This article includes various techniques used for the particle engineering such as Micronization, Spray drying, high pressure homogenization, Supercritical fluid technology and freeze drying. Article also covers the different uses of particle engineering in pharmaceutical industry.


Keywords


Cocrystals, Micronization, Particle Engineering, Pulmonary Drug Delivery, Solubility, Stability

References