Asian Journal of Pharmacy and Technology

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Salubrious Effect of Ethanolic Extract of Cassia auriculata Linn., in Streptazotocin-Nicotinamide Induced Diabetes in Rat Model


Affiliations
1 Venkateswara Institute of Pharmaceutical Sciences, Cherlapally, Nalgonda – 508 001, A.P, India
     

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The ethanolic extract of Cassia auriculata L. flower (family Leguminaceae) were tested for type 2 anti-diabetic activity using streptazotocin - nicotinamide induced diabetic rats and compared with standard. The result expressed that ethanolic extract had shown significant protection and maximum reduction in blood glucose was observed in streptazotocin - nicotinamide induced diabetic rats (p>0.05). The result of this comprehensive study reveals that Cassia auriculata flower shown statistically significant type 2 anti-diabetic activity in comparison to the standard glibenclamide.

Keywords

Cassia auriculata, Anti-Diabetic Activity, Streptazotocin, Nicotinamide and Glibenclamide.
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  • Salubrious Effect of Ethanolic Extract of Cassia auriculata Linn., in Streptazotocin-Nicotinamide Induced Diabetes in Rat Model

Abstract Views: 249  |  PDF Views: 0

Authors

Sharada Nalla
Venkateswara Institute of Pharmaceutical Sciences, Cherlapally, Nalgonda – 508 001, A.P, India
Venkateswarlu Goli
Venkateswara Institute of Pharmaceutical Sciences, Cherlapally, Nalgonda – 508 001, A.P, India
Manoranjan Sabat
Venkateswara Institute of Pharmaceutical Sciences, Cherlapally, Nalgonda – 508 001, A.P, India
Someshwar Komati
Venkateswara Institute of Pharmaceutical Sciences, Cherlapally, Nalgonda – 508 001, A.P, India
M. D. Noorunnisa Begam
Venkateswara Institute of Pharmaceutical Sciences, Cherlapally, Nalgonda – 508 001, A.P, India
Venugopal Rao Kokkirala
Venkateswara Institute of Pharmaceutical Sciences, Cherlapally, Nalgonda – 508 001, A.P, India

Abstract


The ethanolic extract of Cassia auriculata L. flower (family Leguminaceae) were tested for type 2 anti-diabetic activity using streptazotocin - nicotinamide induced diabetic rats and compared with standard. The result expressed that ethanolic extract had shown significant protection and maximum reduction in blood glucose was observed in streptazotocin - nicotinamide induced diabetic rats (p>0.05). The result of this comprehensive study reveals that Cassia auriculata flower shown statistically significant type 2 anti-diabetic activity in comparison to the standard glibenclamide.

Keywords


Cassia auriculata, Anti-Diabetic Activity, Streptazotocin, Nicotinamide and Glibenclamide.