Asian Journal of Pharmacy and Technology

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Assessment of Phytochemical Screening, Antioxidant and Antibacterial Potential of the Methanolic Extract of Ricinus communis l.


Affiliations
1 Suresh Gyan Vihar University, Jaipur, India
2 Mahatma Gandhi Institute of Applied Sciences, JECRC Campus, Jaipur-22, India
     

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The medicinal plants represent a massive reservoir of probable microbial compounds that could be useful as a substitute to synthetic microbicides as well as are being used to develop drugs. In the present study, the powder extracts of Ricinus communis L. (Euphorbiaceae) were tested for their antioxidant activity by radical scavenging activity using 1,1‐diphenyl‐2‐picrylhydrazyl (DPPH) method and antibacterial acitivity against different bacteria i.e. Shigella flexneri, Staphylococcus aureus, Salmonella typhi, Pseudomonas aeruginosa, Klebsiella pneumonia, Proteus vulgaris, Enterobacter aerogenes, Aspergillus niger, Candida albicans, Trichophyton rubrum by disc diffusion method. Also, Phytochemical screening of methanolic extracts of Ricinus communis have been screened. Further, the antioxidant activity shows moderate to potent antioxidant activity, with the ED50 value i.e. 0.838 μg/ml. When screening for antimicrobial activity, the results were expressed in terms of the diameter of the inhibition zone: The maximum efficacy of methanolic extract was showed against Enterobacter and Aspergillus niger.

Keywords

Antioxidant Activity, Antimicrobial Activity, DPPH Scavenging,Ricinus communis
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  • Assessment of Phytochemical Screening, Antioxidant and Antibacterial Potential of the Methanolic Extract of Ricinus communis l.

Abstract Views: 407  |  PDF Views: 1

Authors

Nidhi Rao
Suresh Gyan Vihar University, Jaipur, India
Sandhya Mittal
Suresh Gyan Vihar University, Jaipur, India
Sudhanshu
Suresh Gyan Vihar University, Jaipur, India
Ekta Menghani
Mahatma Gandhi Institute of Applied Sciences, JECRC Campus, Jaipur-22, India

Abstract


The medicinal plants represent a massive reservoir of probable microbial compounds that could be useful as a substitute to synthetic microbicides as well as are being used to develop drugs. In the present study, the powder extracts of Ricinus communis L. (Euphorbiaceae) were tested for their antioxidant activity by radical scavenging activity using 1,1‐diphenyl‐2‐picrylhydrazyl (DPPH) method and antibacterial acitivity against different bacteria i.e. Shigella flexneri, Staphylococcus aureus, Salmonella typhi, Pseudomonas aeruginosa, Klebsiella pneumonia, Proteus vulgaris, Enterobacter aerogenes, Aspergillus niger, Candida albicans, Trichophyton rubrum by disc diffusion method. Also, Phytochemical screening of methanolic extracts of Ricinus communis have been screened. Further, the antioxidant activity shows moderate to potent antioxidant activity, with the ED50 value i.e. 0.838 μg/ml. When screening for antimicrobial activity, the results were expressed in terms of the diameter of the inhibition zone: The maximum efficacy of methanolic extract was showed against Enterobacter and Aspergillus niger.

Keywords


Antioxidant Activity, Antimicrobial Activity, DPPH Scavenging,Ricinus communis

References