Asian Journal of Research in Chemistry

Open Access Open Access  Restricted Access Subscription Access
Open Access Open Access Open Access  Restricted Access Restricted Access Subscription Access

Pharmacological and Synthetic Profile of 1, 2, 4-Triazoles


Affiliations
1 Department of Pharmaceutical Chemistry, Pravara Rural College of Pharmacy, Loni, MS-413736, India
2 Department of Pharmaceutical Chemistry, R.G.Sapkal College of Pharmacy, Nashik, M.S., India
3 Department of pharmaceutical Chemistry, S.N.D. College of Pharmacy, Yeola, Dist-Nashik, MS, India
4 Department of Pharmaceutical Sciences and Research, Bhagwant University, Ajmer, Rajasthan, India
     

   Subscribe/Renew Journal


Triazole is a five membered heterocyclic system consisting of two carbon atoms and three nitrogen atoms shows wide range of biological activities. Triazoles can be synthesized using Einhorn-Brunner reaction or the Pellizzari reaction from acyl hydrazides. Triazoles posses wide spectrum of biological activities like including antibacterial, antifungal, antiviral, anti-inflammatory, anticonvulsant, antidepressant, antihypertensive, analgesic, and hypoglycemic properties. The present reviews attempted to gather the various developments in synthesis and biological activities of triazole derivatives.

Keywords

1, 2, 4-Triazole, Pharmacological Activity, SAR, Total Synthesis.
Subscription Login to verify subscription
User
Notifications
Font Size


Abstract Views: 264

PDF Views: 0




  • Pharmacological and Synthetic Profile of 1, 2, 4-Triazoles

Abstract Views: 264  |  PDF Views: 0

Authors

Nachiket S. Dighe
Department of Pharmaceutical Chemistry, Pravara Rural College of Pharmacy, Loni, MS-413736, India
Ravindra B. Saudagar
Department of Pharmaceutical Chemistry, R.G.Sapkal College of Pharmacy, Nashik, M.S., India
Ramesh S. Kalkotwar
Department of pharmaceutical Chemistry, S.N.D. College of Pharmacy, Yeola, Dist-Nashik, MS, India
D. A. Jain
Department of Pharmaceutical Sciences and Research, Bhagwant University, Ajmer, Rajasthan, India

Abstract


Triazole is a five membered heterocyclic system consisting of two carbon atoms and three nitrogen atoms shows wide range of biological activities. Triazoles can be synthesized using Einhorn-Brunner reaction or the Pellizzari reaction from acyl hydrazides. Triazoles posses wide spectrum of biological activities like including antibacterial, antifungal, antiviral, anti-inflammatory, anticonvulsant, antidepressant, antihypertensive, analgesic, and hypoglycemic properties. The present reviews attempted to gather the various developments in synthesis and biological activities of triazole derivatives.

Keywords


1, 2, 4-Triazole, Pharmacological Activity, SAR, Total Synthesis.