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Synthesis and Characterization of Novel Pyridazinone Derivatives with 5-Mercapto Tetrazole


Affiliations
1 Department of Chemistry, Islamiah College, Vaniyambadi - 635 751, Tamil Nadu, India
2 Department of Chemistry, Thiruvalluvar University, Vellore, Tamil Nadu, India
     

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A simple and efficient experimental procedure for the synthesis of novel pyridazinone derivatives containing 5-mercaptoTetrazole moiety was developed in the presence of several Aryl/alkyl halides and sodium hydride using Dry tetrahydrofuran (as a solvent). The structures of the newly synthesized compounds were characterized by 1HNMR, IR, LCMS data, elemental analysis and melting point.

Keywords

6-(1-Benzyl-1-H-Tetrazol-5-Ylthio)-4, 5-Dimethylpyridazin-3-ol; 5-Mercapto Tetrazole, Triethylamine, Aryl/Alkyl Halide.
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  • Synthesis and Characterization of Novel Pyridazinone Derivatives with 5-Mercapto Tetrazole

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Authors

Kumaran Kubendiran
Department of Chemistry, Islamiah College, Vaniyambadi - 635 751, Tamil Nadu, India
Jaisankar Raguraman
Department of Chemistry, Islamiah College, Vaniyambadi - 635 751, Tamil Nadu, India
S. Raja Mohamed Kamil
Department of Chemistry, Islamiah College, Vaniyambadi - 635 751, Tamil Nadu, India
S. Syed Shafi
Department of Chemistry, Thiruvalluvar University, Vellore, Tamil Nadu, India

Abstract


A simple and efficient experimental procedure for the synthesis of novel pyridazinone derivatives containing 5-mercaptoTetrazole moiety was developed in the presence of several Aryl/alkyl halides and sodium hydride using Dry tetrahydrofuran (as a solvent). The structures of the newly synthesized compounds were characterized by 1HNMR, IR, LCMS data, elemental analysis and melting point.

Keywords


6-(1-Benzyl-1-H-Tetrazol-5-Ylthio)-4, 5-Dimethylpyridazin-3-ol; 5-Mercapto Tetrazole, Triethylamine, Aryl/Alkyl Halide.