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Synthesis, Characterization and Electrochemical Behavior of Transition Metal (II) Complexes from 2, 6-Diphenyl-Piperidin-4-Thiosemicarbazone and their Antimicrobial Studies


Affiliations
1 P.G. and Research Dept. of Chemistry, Jamal Mohamed College, Tiruchirappalli-620020, Tamil Nadu, India
2 Department of Chemistry, Urumu Dhanalakshmi College, Tiruchirappalli-620019, Tamil Nadu, India
     

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2,6-dipheyl-piperidin-4-thiosemicarbazone (DPPTSC) ligand and their metal (CoII, NiII, CuII, CdII) complexes have been synthesized and characterized by IR, 1H NMR, elemental analysis, molar conductance, magnetic susceptibility measurements. The electrochemical property was studied by cyclic voltammeter. All the metal complexes are [ML2Cl2] type, where M= Co, Ni Cu, Cd and L=DPPTSC act as a bidentate ligand in all the complexes. Distorted octahedral geometry for Cu complex and octahedral geometries for all other complexes are proposed. The newly synthesized metal complexes have been screened at in vitro for their antimicrobial activity against five bacterial strains and five fungai strains, all the complexes and ligand CPPTSC possess strong inhibitory action against bacteria and fungi, the antimicrobial activities of the complexes are stronger than those of ligand CPPTSC itself.

Keywords

2, 6-Diphenyl-Piperidin-4-Thiosemicarbazone, Transition Metal (II) Complexes, Spectral Study, Electrochemical Behavior, Antibacterial Activity.
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  • Synthesis, Characterization and Electrochemical Behavior of Transition Metal (II) Complexes from 2, 6-Diphenyl-Piperidin-4-Thiosemicarbazone and their Antimicrobial Studies

Abstract Views: 234  |  PDF Views: 0

Authors

A. Jamal Abdul Nasser
P.G. and Research Dept. of Chemistry, Jamal Mohamed College, Tiruchirappalli-620020, Tamil Nadu, India
A. Pasupathy
Department of Chemistry, Urumu Dhanalakshmi College, Tiruchirappalli-620019, Tamil Nadu, India
R. Surendra Kumar
P.G. and Research Dept. of Chemistry, Jamal Mohamed College, Tiruchirappalli-620020, Tamil Nadu, India
A. Idhayadhulla
P.G. and Research Dept. of Chemistry, Jamal Mohamed College, Tiruchirappalli-620020, Tamil Nadu, India

Abstract


2,6-dipheyl-piperidin-4-thiosemicarbazone (DPPTSC) ligand and their metal (CoII, NiII, CuII, CdII) complexes have been synthesized and characterized by IR, 1H NMR, elemental analysis, molar conductance, magnetic susceptibility measurements. The electrochemical property was studied by cyclic voltammeter. All the metal complexes are [ML2Cl2] type, where M= Co, Ni Cu, Cd and L=DPPTSC act as a bidentate ligand in all the complexes. Distorted octahedral geometry for Cu complex and octahedral geometries for all other complexes are proposed. The newly synthesized metal complexes have been screened at in vitro for their antimicrobial activity against five bacterial strains and five fungai strains, all the complexes and ligand CPPTSC possess strong inhibitory action against bacteria and fungi, the antimicrobial activities of the complexes are stronger than those of ligand CPPTSC itself.

Keywords


2, 6-Diphenyl-Piperidin-4-Thiosemicarbazone, Transition Metal (II) Complexes, Spectral Study, Electrochemical Behavior, Antibacterial Activity.