Asian Journal of Research in Chemistry

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Synthesis and Anti-Inflammatory Activity of 2-Acetyl Thiophene


Affiliations
1 Dept. of Pharmaceutical Chemistry, Sree Siddaganga College of Pharmacy, B.H. Road, Tumkur-572102, Karnataka, India
     

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Some new chalcones have been synthesized by the condensation of 2-acetyl thiophene with various aromatic aldehydes in 40% alkali. The synthesized compounds were identified by spectral data and screened for anti-inflammatory activity. Some of these compounds showed moderate to considerable anti-inflammatory activity.

Keywords

Chalcone, Synthesis, Anti-Inflammatory Activity.
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  • Synthesis and Anti-Inflammatory Activity of 2-Acetyl Thiophene

Abstract Views: 205  |  PDF Views: 0

Authors

B. Ramesh
Dept. of Pharmaceutical Chemistry, Sree Siddaganga College of Pharmacy, B.H. Road, Tumkur-572102, Karnataka, India
B. Someswara Rao
Dept. of Pharmaceutical Chemistry, Sree Siddaganga College of Pharmacy, B.H. Road, Tumkur-572102, Karnataka, India
S. V. Kulkarni
Dept. of Pharmaceutical Chemistry, Sree Siddaganga College of Pharmacy, B.H. Road, Tumkur-572102, Karnataka, India

Abstract


Some new chalcones have been synthesized by the condensation of 2-acetyl thiophene with various aromatic aldehydes in 40% alkali. The synthesized compounds were identified by spectral data and screened for anti-inflammatory activity. Some of these compounds showed moderate to considerable anti-inflammatory activity.

Keywords


Chalcone, Synthesis, Anti-Inflammatory Activity.