Asian Journal of Research in Chemistry

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Synthesis of N-Bases from Primitive Earth Gases in presence and absence of Metal Ferrocyanides


Affiliations
1 Department of Chemistry, SSMMUSSS Govt. P.G College Dwarahat, Almora, Uttarakhand, India – 263653., India
2 Department of Chemistry, DSB Campus, Nainital, Uttarakhand., India
     

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The action of heat on Acetylene, Ammonia and Water vapour in presence and absence of metal ferrocyanides at 90±5°C under simulated sea beach conditions has been investigated for the plausible formation of nucleic acid bases. Paper chromatography (PC) and High-Performance Liquid Chromatography (HPLC) analysis of the reaction concentrate heated up to 200hrs revealed purine and pyrimidine bases viz. cytosine, uracil, adenine, thymine and hypoxanthine were formed and confirmed with the data of authentic samples.

Keywords

Metal ferrocyanides, Nucleic acid bases, Prebiotic, Paper chromatography, High Performance Liquid Chromatography.
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  • Oparin A.I. Origin of Life (Translated from Russian By S. Morgolis) Dover Publication, New York, (1953).1936

  • Oparin A.I. Proiskhozhdenie Zhizny. Isd. Moskovshii, Raochii, Moscow.1924

  • Haldane, J.B.S. The Rationalist Annual. 1929

  • D Bharti, C Arora. Synergistic Effect of Antifungal Activity of Medicinal Plants with Transition Metal Ferrocyanides. Asian J.Research Chem. .2011

  • Kuhn, W. Chem. Ber. 1956. pp. 89-303.

  • Bernal, J.D. The Physical basis of Life Routledge and Kegan Paul, London. 1951

  • Miller, S.L., and Orgel, L.E. The origin of Life on the Earth. Prentice Hall, Inc Englewood Cliffs, New Jersey. 1974

  • Rutten M.G. The Origin of Life, Elsevier Publishing company, Amesterdam London, New York. 1971

  • Lemmon, R.M. Chemical evolution, Chem. Rev. 1970. pp. 70,95-109.

  • Ferris J. P. Origin of Life and Evolution of Biosphere. 1922 pp. 22,109-134.

  • R. Vijayalakshmi, S. Anbazhagan. Method Development and Validation for Simultaneous Estimation of Metamizole Sodium and Pitofenone HCl by a Stability Indicating RP-HPLC. Asian J. Research Chem. 2011.

  • Von domm, K.L, Grant B. and Edmond, J.M. NATO conference series, Ser IV Marine Science, Vol 12 New York. 1983. pp. 391-409.

  • K Gururani, C K Pant, H.D. Pathak. Thermal Synthesis of Amino Acids from Acetonitrile - Water Vapor in Presence and Absence of Metal Oxides (Silica and Alumina) Under Prebiotic Wetting and Drying Conditions of Primitive Earth. Asian J. Research Chem. 2013

  • Pandey, N. Ph.D. Thesis, Kumaun University, Nainital. 2011

  • Kavita Gururani. et al. Heat induced synthesis of Amino Acids from reaction system comprised of Acetylene, Ammonia and water vapour in presence and absence of metal oxides (silica and alumina) under wetting drying conditions of primitive earth. Asian J. Research Chem.5(9). September. 2012.

  • Edmond, J.M and Von Damn, K.L. Nature McDuff. R.E. and Measures, C.I. 1982. pp. 297, 187- 191

  • Pant, A.K. Ph.D. Thesis, Kumaun University, Nainital. 1978

  • Pathak, C.K. Ph.D. Thesis, Kumaun University, Nainital. 1979

  • Kalra, S. Ph.D. Thesis, Kumaun University, Nainital. 1999

  • Bargali. K. Ph.D. Thesis, Kumaun University, Nainital. 2004

  • Hemlata. Ph.D. Thesis, Kumaun University, Nainital. 2005

  • Arrhenius, G. Clay Minerals and the origin of Life (eds. A.G. CairnsSmith and H. Hartman) Cambridge university press, Cambridge, 1986.pp 97-104.

  • Egami, F. J. Biochem. 1957. pp. 77,1165.

  • Schwendinger, M.G. & Rode B.M. Inorg. Chem. Acta. 1991. pp. 186, 247-251.

  • Ponnamperuma, C., Shimoyama, A and Fribele, E. Origin of Life.1982. pp. 12, 9-40.

  • Lambert, J.F. Origins of Life Evol. Biosphere. 2008. pp. 38, 211-242.

  • Kourim, V. Raise and B. Millions, J. Inorg, Nucl.Chem. 26. 1964. pp.1111.

  • Subhasish Chaudhur, Biswajit Chandra Das. Detection of Commonly used Carbamates by Thin Layer Chromatography and Spot TestMethod Asian J. Research Chem. 2012.

  • Punam S. Desai et al. High Performance Liquid Chromatography – A Validation View. Asian J PAna.2019.

  • Sravani A. A Review Article on Flash Chromatography. Asian J. Research Chem. 2018.

  • Hancock, W.S. and Hardling D.R.K. CRC Handbook of HPLC for separation of amino acids, peptides, proteins and nucleic acid. 1982.

  • Shinde Ganesh et al. A Review on Chromatography and Advancement in Paper Chromatography Technique. Asian J PAna. 2021

  • H.C. Urey. "The Planets" Yale Univ. Press, New Haven, 1952. pp. 254

  • NKD Devi et al. A Friendly Relationship between Man and Microbes.Research J Science & Technology. 2010

  • Egami, F. J.Molec. Evol, 4. 1974. pp. 113- 191

  • Miller, S.L. J.Amer. Chem. Soc.77(9). 1995. pp. 2351-2361.

  • Jai Devi, Nisha Batra, Rajesh Malhotra. Biological Evaluation of Co (II), Ni(II), Cu(II) and Zn(II) complexes derived from Hydrazide Ligand. Asian J. Research Chem. 2017 .


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  • Synthesis of N-Bases from Primitive Earth Gases in presence and absence of Metal Ferrocyanides

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Authors

Namrata Pandey
Department of Chemistry, SSMMUSSS Govt. P.G College Dwarahat, Almora, Uttarakhand, India – 263653., India
Chandra Kala Pant
Department of Chemistry, DSB Campus, Nainital, Uttarakhand., India

Abstract


The action of heat on Acetylene, Ammonia and Water vapour in presence and absence of metal ferrocyanides at 90±5°C under simulated sea beach conditions has been investigated for the plausible formation of nucleic acid bases. Paper chromatography (PC) and High-Performance Liquid Chromatography (HPLC) analysis of the reaction concentrate heated up to 200hrs revealed purine and pyrimidine bases viz. cytosine, uracil, adenine, thymine and hypoxanthine were formed and confirmed with the data of authentic samples.

Keywords


Metal ferrocyanides, Nucleic acid bases, Prebiotic, Paper chromatography, High Performance Liquid Chromatography.

References