Asian Journal of Research in Chemistry

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Amino-indane: Fused Heterocycle with Diverse Pharmacological Activity


Affiliations
1 Department of Pharma. Chemistry, Parul Institute of Pharmacy, Limda-391 760, Vadodara, Gujarat, India
2 Darshan Pharma Chem, Plot No. A-1/3621, GIDC Estate, Ankeleshwar Gujarat, India
     

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Amino-indane is an important structural moiety found in numerous pharmaceutically active compounds. Aminoindane has non-heterocyclic fused ring having six member benzene ring and five member cyclopentane ring with amino group. Amino-indane derivatives play a vital role in the field of medicinal chemistry. This has the important place to synthesis of class of different pharmacological activities. Amino-indane moiety is an important pharmacophore and exhibits outstanding biological activities. A number indane derivatives have acquired a special place in heterocyclic field because of their diversified activities such as antimicrobial, antipyretic, analgesic, anticonvulsant, CNS Depressant anti-inflammatory, anticancer activity. This review emphasized the recent researches in amino-indanes in various diseases and disorders.

Keywords

Indane, Amino-indane, Anti-inflammatory, Pharmacological Activity
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  • Amino-indane: Fused Heterocycle with Diverse Pharmacological Activity

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Authors

Prafulla M Sabale
Department of Pharma. Chemistry, Parul Institute of Pharmacy, Limda-391 760, Vadodara, Gujarat, India
Meeraben P. Kakadiya
Department of Pharma. Chemistry, Parul Institute of Pharmacy, Limda-391 760, Vadodara, Gujarat, India
Jitendra G. Dobariya
Darshan Pharma Chem, Plot No. A-1/3621, GIDC Estate, Ankeleshwar Gujarat, India

Abstract


Amino-indane is an important structural moiety found in numerous pharmaceutically active compounds. Aminoindane has non-heterocyclic fused ring having six member benzene ring and five member cyclopentane ring with amino group. Amino-indane derivatives play a vital role in the field of medicinal chemistry. This has the important place to synthesis of class of different pharmacological activities. Amino-indane moiety is an important pharmacophore and exhibits outstanding biological activities. A number indane derivatives have acquired a special place in heterocyclic field because of their diversified activities such as antimicrobial, antipyretic, analgesic, anticonvulsant, CNS Depressant anti-inflammatory, anticancer activity. This review emphasized the recent researches in amino-indanes in various diseases and disorders.

Keywords


Indane, Amino-indane, Anti-inflammatory, Pharmacological Activity

References