Asian Journal of Research in Chemistry

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Pharmacological Activities of Benzimidazole Derivatives - An Overview


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1 Kamla Nehru Institute of Management & Technology (Faculty of Pharmacy, Department of Pharmaceutical Chemistry), Faridipur, Sultanpur, Uttar Pradesh, India
     

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Benzimidazole derivates play vital role in biological field such as antimicrobial, antiviral, antidiabetic, and anticancer activity. Therapeutic Significance of these clinically useful drugs in treatment of microbial infections encouraged the development of some more potent and significant compounds. Benzimidazoles are remarkably effective compounds both with respect to their bacteria inhibitory activity and their favorable selectivity ratio. Extensive biochemical and pharmacological studies have confirmed that these molecules are effective against various strains of microorganisms. This comprehensive overview summarizes the chemistry of different derivatives of substituted benzimidazole along with their antimicrobial activity.

Keywords

Substituted Benzimidazoles, Therapeutic Significance, Antimicrobial Activity
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  • Pharmacological Activities of Benzimidazole Derivatives - An Overview

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Authors

Rohit Tripathi
Kamla Nehru Institute of Management & Technology (Faculty of Pharmacy, Department of Pharmaceutical Chemistry), Faridipur, Sultanpur, Uttar Pradesh, India
Arvind Kumar Singh
Kamla Nehru Institute of Management & Technology (Faculty of Pharmacy, Department of Pharmaceutical Chemistry), Faridipur, Sultanpur, Uttar Pradesh, India
Vipul Singh
Kamla Nehru Institute of Management & Technology (Faculty of Pharmacy, Department of Pharmaceutical Chemistry), Faridipur, Sultanpur, Uttar Pradesh, India
Preety Mishra
Kamla Nehru Institute of Management & Technology (Faculty of Pharmacy, Department of Pharmaceutical Chemistry), Faridipur, Sultanpur, Uttar Pradesh, India
Roopesh Maurya
Kamla Nehru Institute of Management & Technology (Faculty of Pharmacy, Department of Pharmaceutical Chemistry), Faridipur, Sultanpur, Uttar Pradesh, India

Abstract


Benzimidazole derivates play vital role in biological field such as antimicrobial, antiviral, antidiabetic, and anticancer activity. Therapeutic Significance of these clinically useful drugs in treatment of microbial infections encouraged the development of some more potent and significant compounds. Benzimidazoles are remarkably effective compounds both with respect to their bacteria inhibitory activity and their favorable selectivity ratio. Extensive biochemical and pharmacological studies have confirmed that these molecules are effective against various strains of microorganisms. This comprehensive overview summarizes the chemistry of different derivatives of substituted benzimidazole along with their antimicrobial activity.

Keywords


Substituted Benzimidazoles, Therapeutic Significance, Antimicrobial Activity

References