Asian Journal of Research in Chemistry

Amit Kumar ¹, Shri Krishna ², Arjun Singh ³

Affiliations
1 Regional Drugs Testing Laboratory, Government of India, Ministry of Health and Family Welfare, Chandigarh, IN
2 Department of Chemistry, Gurukula Kangari University, Haridwar, IN
3 Central Council of Research in Ayurveda and Sidha, Government of India, Ministry of Health and Family Welfare, Janakpuri, New Delhi, IN

Abstract

Present studies were carried out to screen Abutilon indicum Linn. (Malvaceae), for the point of view of its mineral analysis. The Plant had found throughout tropical and subtropical regions. The plant was mentioned in Indian Meteria medica which is commonly used in the indigenous system of medicine under the name "Atibala" in various ailments. The plant is used to treat various types of ailments and diseases such as neurological disorders, epistaxis and heart diseases as astringent, diuretic demulcent, in rheumatism and post delivery complaints in cattle. Leaves are used in toothache as demulcent, in gonorrhoea inflammation and wounds for stomachache, diabetes, diarrhoea, hydrococle Jaundice, boil, piles headache as a tonic in rheumatism and as an antipyretic agent. Elemental analysis indicated that plant had the sufficient presence of minerals. The nine elements Na, K, Ca, Mg, Fe, Cu, Co, Mn and Ni were determined in all parts of plant ash. The present investigation of mineral elements was carried out using AAS&ICP techniques. While some physico-chemical parameters viz. physical state, colour, taste, total ash content, ash value (water, acid and alcohol soluble), pH and moisture content were also studied. It showed the presence of different minerals, which can be suggested for therapeutic efficacy and vitality as dietary supplement.

Keywords

Abutilon indicum Linn, Mineral Elements, AAS, ICP, Dietary Supplements.

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Arjun Singh ¹, Ajay Kr. Meena ², M. M. Rao ², Sudeep Mishra ¹, M. M. Padhi ¹, Ramesh Babu ¹

Affiliations
1 Central Council for Research in Ayurveda and Siddha, Janakpuri, Delhi-110058, IN
2 National Institute of Ayurvedic Pharmaceutical Research, Patiala - 47001, Punjab, IN

Abstract

Herbal drugs are traditionally used in various parts of the world to cure different diseases. The present study has been conducted to evaluate the quality control parameters of the hydro alcoholic extracts of Tephrosia purpurea Linn ;an important Indian medicinal plant widely used in the preparation of Ayurvedic formulations. Tephrosia purpurea Linn. is a highly branched, sub-erect herb commonly known in Sanskrit as Sharapunkha. It has been used in Indian traditional medicine for the treatment of various inflammatory disorders. The plant is used to cure diseases of the kidney, liver, spleen, heart, blood, skin eruptions, bronchitis, bilious febrile attack, boils, pimples, and bleeding piles. The dried herb is effective as a tonic, laxative, and diuretic. The ischolar_mains and seeds are have insecticidal, piscicidal and vermifugal properties.

As there is no detailed standardisation work reported on Tephrosia purpurea Linn extract, the physicochemical parameters, phytochemical analysis, toxic heavy metals and microbial contamination analysis are carried out. The study revealed specific identities for the particular crude drug which will be useful in identification and control to adulterations of the raw drug and Ayurvedic formulations.

Keywords

Tephrosia purpurea Linn, Ayurvedic, Physicochemical Parameters, Toxic Metals.

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Ajay Kumar Meena ¹, Uttam Singh ², Arjun Singh ³, Sudeep Mishra ³, M. M. Rao ¹, M. M. Padhi ³, Ramesh Babu ³, A. Gaurav ²

Affiliations
1 National Institute of Ayurvedic Pharmaceutical Research, Patiala- 147001, Punjab, IN
2 School of Pharmaceutical Sciences, Shobhit University, Meerut, UP, IN
3 Central Council for Research in Ayurveda and Siddha (CCRAS), Janakpuri, Delhi-110058, IN

Abstract

Vitex negundo Linn (Five-leaved chaste tree), Hindi-Nirgundi, Sanskrit-Sindhuvara, Tamil and Malyalam-Vennochi, Telugu-Nalla vavili and Punjabi-Marwan (Family: Verbenaceae), is an important medicinal plant found throughout India. All parts of this plant especially the leaf and ischolar_main extracts are being used in various formulations in Ayurveda and Unani systems of medicine. Vitex negundo Linn is pungent, bitter and astringent in taste and according to Ayurveda , it alleviates vata and kapha doshas, but aggravates pitta dosha. It possesses light and dry attributes. Its leaves and seeds are widely used externally for rheumatism and inflammations of joints and also reported to have insecticidal properties. Internally, decoction of its leaves is taken as diuretic, expectorant, vermifuge, tonic and febrifuge. The chemical components of the essential oil of leaf isolated from the plant are used to treat colds and coughing spells. Vitex negundo Linn is used in Classical Ayurvedic Preparations like Nirgundi kalka, Nirgundi ghrta, Nirgundi kvatha, Vranasodhana taila, Visagarbha taila etc. The evaluation studies of Pharmacopoeial standards, phytochemical parameters suggested that the observed physiochemical parameters are of great value in quality control and formulation development of Vitex negundo Linn. Physicochemical parameters like preliminary characteristics, toxic heavy metals, and aflatoxin analysis were carried out. The study revealed that the results on different parameters of the crude drug will be useful in identification and control of adulterations.

Keywords

Ayurveda, Vitex negundo Linn, Toxic Metals, Aflatoxin and Quality Control.

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