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Authors
Affiliations
1 KYDSCT’s College of Pharmacy, Sakegaon, Tal. Bhusawal, Dist. Jalgaon, (M.S), IN
2 TVES’s College of Pharmacy, Faizpur, Tal. Yawal, Dist. Jalgaon, (M.S), IN
Source
Asian Journal of Research in Chemistry, Vol 2, No 2 (2009), Pagination: 157-161
Abstract
A series of N’-[3-(aryl/alkyl substituted)-4-oxo-1, 3-thiazolidin-2-ylidene]-2-(pyridine-2-yloxy) acetohydrazides were synthesized using appropriate synthetic route. These compounds were synthesized by their analytical and spectral data. All the newly synthesized compounds were examined for their antidiabetic activity using GOD-POD method on Wistar strain rats. The acute toxicity study (LD50) values of these compounds were determined. The test compounds showed significant antidiabetic activity on evaluation.
Keywords
Thiazolidinone, Pyridine, Antidiabetic Activity.