Asian Journal of Research in Chemistry

P. E Etusim ¹, E.E Okafor, ¹, N.C Nwachukwu, ², P. E Melariri, ³, C.I Ogbonnaya ⁴

Affiliations
1 Unit of Medical Parasitology and Environmental Sciences, Faculty of Biological and Physical Sciences, Abia State University, Uturu
2 Unit of Medical Microbiology and Parasitology, Faculty of Biological and Physical Sciences, Abia State University, Uturu
3 Division of Pharmacology, Department of Medicine, University of Cape Town Medical School K45, Old Main Building Gischolar_maine Hospital, Observatory 7925, ZA
4 Unit of Plant Taxonomy and Ecotoxicology, Department of Plant Science and Biotechnology, Faculty of Biological and Physical Sciences, Abia State University, Uturu

Abstract

This study is provoked by the paucity of information on the antibacterial or pharmacological activities of Aloe vera stems and ischolar_mains. The antibacterial activity of Aloe vera leaf, stem and ischolar_main extracts on three organisms (Pseudomonas aeruginosa, Salmonella typhi and Proteus mirabilis) was investigated using agar well diffusion method. The Aloe vera leaf extract proved to be most effective. Both Aloe vera leaf Cold Water Extract (CWE) and Ethanol Crude Extract (ECE) demonstrated significant antibacterial activity against the sampled organisms. CWE of Aloe vera stem showed no antibacterial activity in the bacterial species while ECE had antibacterial activity on Pseudomonas aeruginosa and Proteus mirabilis. The ischolar_main CWE and ECE only exhibited antibacterial activity on Proteus mirabilis. The stems had no antibacterial activity on Salmonella typhi and Pseudomonas aeruginosa. The extract with the highest antibacterial properties was ECE of Aloe vera ischolar_mains. There is therefore a need for the inclusion of Aloe vera ischolar_mains in Aloe vera antibacterial efficacy studies.

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