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Hipparagi, S. M.
- Synthesis, Anti-bacterial, Anti-fungal and Anti-inflammatory Activities of some Novel 3, 5-Diaryl-1-Aryl Pyrazoline Derivatives
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PDF Views:2
Authors
Affiliations
1 Research Scholar, Bhagwant University, Ajmer and Department of Pharmaceutical Chemistry, Maratha Mandal’s College of Pharmacy, Belgaum. 590 016
2 Department of Pharmaceutical Chemistry, KLE University’s, College of Pharmacy, Rajajinagar, Bangalore-40
1 Research Scholar, Bhagwant University, Ajmer and Department of Pharmaceutical Chemistry, Maratha Mandal’s College of Pharmacy, Belgaum. 590 016
2 Department of Pharmaceutical Chemistry, KLE University’s, College of Pharmacy, Rajajinagar, Bangalore-40
Source
Asian Journal of Research in Chemistry, Vol 6, No 7 (2013), Pagination: 618-622Abstract
4-substituted acetanilide on treatment with substituted benzaldehyde affords the corresponding chalcones (C<SUB>13</SUB>-C<SUB>24</SUB>). Further treatment of chalcones with phenylhydrazine undergone cyclocondensation and gave a new series of novel 3, 5-Diaryl-1-aryl-2- pyrazoline (P13-P24). All synthesized compounds were screened for their antibacterial and antifungal activity at 75μg concentration and anti-inflammatory activity at 200mg/ kg body weight. Some of the compounds have shown excellent activityKeywords
Pyrazoline, Antibacterial, Antifungal, Anti-tubercular Activity
References
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- Synthesis and Evaluation of Substituted Aromatic Formazans for their Antimicrobial Activities
Abstract Views :185 |
PDF Views:1
Authors
Affiliations
1 Department of Pharmaceutical Chemistry, KLES’ College of Pharmacy, Belgaum-590010, Karnataka, IN
2 KLES’ College of Pharmacy, Bangalore-560010, Karnataka, IN
3 Department of Pharmaceutical Chemistry, KLES’ College of Pharmacy, Bangalore-560010, Karnataka, IN
1 Department of Pharmaceutical Chemistry, KLES’ College of Pharmacy, Belgaum-590010, Karnataka, IN
2 KLES’ College of Pharmacy, Bangalore-560010, Karnataka, IN
3 Department of Pharmaceutical Chemistry, KLES’ College of Pharmacy, Bangalore-560010, Karnataka, IN
Source
Asian Journal of Research in Chemistry, Vol 4, No 2 (2011), Pagination: 200-202Abstract
A series of substituted aromatic formazans were synthesized and evaluated for antimicrobial activities. All the structures of newly synthesized compounds were confirmed by their IR, 1HNMR and LC-MS analysis. Newly synthesized substituted aromatic formazans have shown promising antimicrobial activities when they were screened.