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Authors
Affiliations
1 Dept. of Pharma. Chemistry, Sree Siddaganga College of Pharmacy, B.H. Road, Tumkur-572102, Karnataka, IN
Source
Asian Journal of Research in Chemistry, Vol 3, No 1 (2010), Pagination: 29-30
Abstract
Some new pyrimidine derivatives were synthesized by reacting chalcones of 2-acetyl thiophene with guanidine hydrochloride in the presence of alcohol. The synthesized compounds were identified by spectral data and screened for anti-inflammatory activity. Some of these compounds showed moderate to considerable anti-inflammatory activity.
Keywords
Synthesis, Pyrimidines, Anti-Inflammatory Activity.