Asian Journal of Research in Pharmaceutical Sciences

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A Review on: Polycystic Ovarian Disorder


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1 Department of Pharmacology, AISSMS College of Pharmacy, Pune, Maharashtra – 411001,, India
     

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Polycystic ovary disorder (PCOD) is hormonal disorder among reproductive-age women. Causing enlarged ovaries with small cysts on the outer edges in patients with PCOD, the secretion rate and metabolism of androgens and estrogens are disrupted. The pathophysiology of the syndrome is complex and there is no single defect from which it is known to result, it is hypothesized that insulin resistance is a key factor. With regards to the increasing prevalence of PCOD and associated mental and physical problemsas well as the effects of changes in sex hormones in development of this disease, our aim is to investigate the effects of synthetic drug and herbal drug in the serum levels of sex hormones and ovarian tissue. Several Pharmacological studies have described the use of various Ayurvedic medicinal plants and their constituents play the important role for the treatment of PCOD.Therefore, this drug can be partly effective in this syndrome via affecting the different hormones and serum levels of ovarian morphology, weight and representing an opportunity to investigate and discovery new bioactive products. This review discussed some synthetic and herbal drug which has the potential for the treatment of PCOD

Keywords

PCOD, Pathophysiology, Risk factor in PCOD, Synthetic Medication, Herbal Medication.
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  • A Review on: Polycystic Ovarian Disorder

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Authors

Omkar A Devade
Department of Pharmacology, AISSMS College of Pharmacy, Pune, Maharashtra – 411001,, India
Rohan D. Londhe
Department of Pharmacology, AISSMS College of Pharmacy, Pune, Maharashtra – 411001,, India
Nisarga V. Sokate
Department of Pharmacology, AISSMS College of Pharmacy, Pune, Maharashtra – 411001,, India
Utkarsha R Randave
Department of Pharmacology, AISSMS College of Pharmacy, Pune, Maharashtra – 411001,, India
Pallavi A Ranpise
Department of Pharmacology, AISSMS College of Pharmacy, Pune, Maharashtra – 411001,, India

Abstract


Polycystic ovary disorder (PCOD) is hormonal disorder among reproductive-age women. Causing enlarged ovaries with small cysts on the outer edges in patients with PCOD, the secretion rate and metabolism of androgens and estrogens are disrupted. The pathophysiology of the syndrome is complex and there is no single defect from which it is known to result, it is hypothesized that insulin resistance is a key factor. With regards to the increasing prevalence of PCOD and associated mental and physical problemsas well as the effects of changes in sex hormones in development of this disease, our aim is to investigate the effects of synthetic drug and herbal drug in the serum levels of sex hormones and ovarian tissue. Several Pharmacological studies have described the use of various Ayurvedic medicinal plants and their constituents play the important role for the treatment of PCOD.Therefore, this drug can be partly effective in this syndrome via affecting the different hormones and serum levels of ovarian morphology, weight and representing an opportunity to investigate and discovery new bioactive products. This review discussed some synthetic and herbal drug which has the potential for the treatment of PCOD

Keywords


PCOD, Pathophysiology, Risk factor in PCOD, Synthetic Medication, Herbal Medication.

References