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Attenuation of Cardiovascular Response to Laryngoscopy and Tracheal Intubation by a Bolus Dose of Intravenous Esmolol and Placebo - A Comparative Study
Laryngoscopy and tracheal intubation produce marked sympathetic responses in susceptible-patients. β-blockers counteract these sympathetic activations. Hence, our study was designed to evaluate and compare esmolol as intravenous bolus to a placebo in attenuating sympathetic responses at laryngoscopy and intubation in healthy adults.
Keywords
Esmolol, Heart Rate, Systolic Blood Pressure, Mean Arterial Pressure, Laryngoscopy, Tracheal Intubation.
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- Shane Sheppard, Chris J. Eagle, Leostrumin. A bolus dose of Esmolol attenuates tachycardia and hypertension after tracheal intubation. Can J Anaesth 1990; 37(2): 202-205.
- Figueredo E, Garcia EM-Fuenter. Assessment of the efficacy of Esmolol on the haemodynamic changes induced by laryngoscopy and tracheal intubation: A metanalysis. Acta Anaesthesiol Scand 2001; 1011.
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