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A Comparative Study of the Efficacy of IV Clonidine Versus IV Dexmedetomidine in Attenuating the Pressor Response during Laryngoscopy and Endotracheal Intubation - A Prospective Randomized Double Blinded Study
Direct laryngoscopy and endotracheal intubation induces a cardiovascular stress response that on an average increases blood pressure by 40-50% and heart rate by 20%. Pre-induction dose of IV Clonidine or IV Dexmedetomidine attenuates the hemodynamic stress response to laryngoscopy and endotracheal intubation.
Keywords
Clonidine, Dexmedetomidine, Intubation, Pressor Response, Attenuation, Recovery.
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- Varshali MK, Sushma L, Ramesh N, Dexmedetomidine attenuates sympathoadrenal response to tracheal intubation & reduces perioperative anesthetic requirement. Indian Journal of Anesthesia, July- August 2011; 55(4):352-7.
- Kulka PJ, Tryba M, Zenz M, Dose – Response of intravenous Clonidine on stress response during induction of anesthesia in coronary artery bypass graft patient. Anesthesia Analgesia, 1995;80:263-8.
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