Annual Review of Physiology

This volume begins with a gripping and refreshing narrative by Terje Lømo in an article entitled 'Scientific discoveries: what is required for lasting impact'. Lømo addresses two broad areas of scientific studies with which he was personally involved. First, a discovery, in this case, long-term potentiation, which though initially slow to gain acceptance and publicity has withstood the test of time, particularly in relation to understanding the physiology of learning and memory in the hippocampus.