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Therapeutic Properties of Processed Aqueous Extract of Asteracantha longifolia in the Human


Affiliations
1 Herbal Science Trust, Bengaluru 560 025, India
2 Department of Biotechnology, Sir M. Visvesvaraya Institute of Technology, Bengaluru 562 157, India
3 Department of Pharmacology, UAS, Bengaluru 560 065, India
 

Treatment of disease with herbal extracts is common in both Ayurveda and herbal systems of medicine. We have identified that therapeutic activity of Asteracantha longifolia is associated with the dialysable portion of the extract. The extract was partially purified by a method using alcohol precipitation. This partially purified A. longifolia extract (PALE) was studied for its therapeutic activity in the human when administered orally. Oral administration of 0.1 ml of PALE (equivalent to 5 ml of original extract) was found to increase haemoglobin and lymphocytes and reduce neutrophils in the blood. The effect was not short term as this profile persisted for as long as 6-8 months, indicating that PALE is an excellent herbal medicament for improving the quality of blood in the human.

Keywords

A. longifolia, Bone Marrow, Herbal Restorative, Lymphocytes.
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  • Therapeutic Properties of Processed Aqueous Extract of Asteracantha longifolia in the Human

Abstract Views: 378  |  PDF Views: 115

Authors

G. Satyanarayana Murthy
Herbal Science Trust, Bengaluru 560 025, India
T. P. Francis
Herbal Science Trust, Bengaluru 560 025, India
C. Rajendra Singh
Department of Biotechnology, Sir M. Visvesvaraya Institute of Technology, Bengaluru 562 157, India
K. Somasundar
Department of Biotechnology, Sir M. Visvesvaraya Institute of Technology, Bengaluru 562 157, India
H. G. Nagendra
Department of Biotechnology, Sir M. Visvesvaraya Institute of Technology, Bengaluru 562 157, India
N. B. Sridhar
Department of Pharmacology, UAS, Bengaluru 560 065, India

Abstract


Treatment of disease with herbal extracts is common in both Ayurveda and herbal systems of medicine. We have identified that therapeutic activity of Asteracantha longifolia is associated with the dialysable portion of the extract. The extract was partially purified by a method using alcohol precipitation. This partially purified A. longifolia extract (PALE) was studied for its therapeutic activity in the human when administered orally. Oral administration of 0.1 ml of PALE (equivalent to 5 ml of original extract) was found to increase haemoglobin and lymphocytes and reduce neutrophils in the blood. The effect was not short term as this profile persisted for as long as 6-8 months, indicating that PALE is an excellent herbal medicament for improving the quality of blood in the human.

Keywords


A. longifolia, Bone Marrow, Herbal Restorative, Lymphocytes.



DOI: https://doi.org/10.18520/cs%2Fv112%2Fi05%2F982-988