Inhibition Spectrum, Purification and Kinetic Study of Alpha-Amylase Inhibitor from Murraya koenigii Endophytic Actinobacterium (Streptomyces koyangensis Strain B025)

Diabetes mellitus type II, the chronic endocrine disorder, affects metabolism of carbohydrates, proteins, fats, electrolytes and water. This type of diabetes can only be controlled by maintaining low levels of blood glucose and through a healthy lifestyle¹. The currently available medicines, viz. biguanides, sulphonylureas and thiazolidinediones, pose risks of secondary failure and prominent side-effects. Therefore, it is imperative to go for the alternative approach, a strong antidiabetic activity, without any spin-off results.