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Annual Review of Nutrition, 2018
This issue of Annual Review of Nutrition (ARN) deals with many unusual nutrients as also with the complex interactions between nutrients. While the nutritional significance of fat-soluble vitamins is well-documented, most researchers tend to focus on the more popular areas, such as vitamin A and vision or vitamin D and bone health. Usually the other vitamins such as vitamin E and vitamin K get downplayed – and this issue of ARN attempts to bridge this gap. Shearer and Okano focus on vitamin K, which is classically known for its role in blood coagulation. The Vitamin K cycle involves its utilization as a cofactor for a microsomal enzyme, γ -carboxyglutamyl carboxylase (GGCX), and its subsequent regeneration by the enzyme Vit K epoxide reductase (VKOR).
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