Current Science

Open Access Open Access  Restricted Access Subscription Access

Antibiotic Abuse:Post-Antibiotic Apocalypse, Superbugs and Superfoods


Affiliations
1 Chemical Biology Group, South Asian University, New Delhi 110 021, India
 

Cases of antibiotic abuse have reached a phenomenal level worldwide and become a global health concern affecting a larger number of people than those affected by the disease itself. Facilitating generation of multidrug- resistant superbugs, antibiotic misuse practices are a pressing issue worldwide, with the threat to developing South Asian countries like India, being insurmountable. This commentary summarizes our knowledge about this global pandemic; its causes, effects and severity, and discusses the preventive measures taken to curb antibiotic abuse. We highlight emergence of superfoods as natural antibiotics (or alternative medicine) that hold potential to change the face of modern therapeutics.
User
Notifications
Font Size

  • Ventola, C. L., Pharm. Ther., 2015, 40, 277.

  • Abdulah, R., Pharm. Regul. Aff., 2012, 1, 1000e1106.

  • Jamal, W. Y., Albert, M. J. and Rotimi, V. O., PLoS ONE, 2016, 11, e0152638.

  • Shaheen, B. W., Nayak, R. and Boothe, D. M., Antimicrob. Agents Chemother., 2013, 57, 2902–2903.

  • Raghunath, D., J. Biosci., 2008, 33, 593– 603.

  • Kumar, S. G. et al., J. Natl. Sci. Biol. Med., 2013, 4, 286.

  • O’Neill, J., Tackling drug-resistant infections globally: Final report and recommendations, HM Government and Wellcome Trust, UK, 2016.

  • Andriole, V. T., Clin. Infect. Dis., 2005, 41, S113–S119.

  • Dutta, S. S., Br. Med. J. (online), 2017, 357.

  • Petrovska, B. B. and Cekovska, S., Pharmacogn. Rev., 2010, 4, 106.

  • Elnima, E., Ahmed, S., Mekkawi, A. and Mossa, J., Die Pharm., 1983, 38, 747– 748.

  • Gul, P. and Bakht, J., J. Food Sci. Technol., 2015, 52, 2272–2279.

  • Zorofchian Moghadamtousi, S. et al., BioMed. Res. Int., 2014.

  • Gupta, A., Mahajan, S. and Sharma, R., Biotechnol. Rep., 2015, 6, 51–55.

  • Nakatsuji, T. et al., J. Invest. Dermatol., 2009, 129, 2480–2488.

  • Bergsson, G., Arnfinnsson, J., Steingrı́msson, Ó. and Thormar, H., Antimicrob. Agents Chemother., 2001, 45, 3209–3212.

  • Cvetnic, Z. and Vladimir-Knezevic, S., Acta Pharm., 2004, 54, 243–250.

  • White Jr, J. W., Subers, M. H. and Schepartz, A. I., Biochim. Biophys., 1963, 73, 57–70.

  • Côté, J., Caillet, S., Dussault, D., Sylvain, J.-F. and Lacroix, M., Food Res. Int., 2011, 44, 2922–2929.

  • Reygaert, W. C., Front. Microbiol., 2014, 5, 434.

  • Lambert, R., Skandamis, P. N., Coote, P. J. and Nychas, G. J., J. Appl. Microbiol., 2001, 91, 453–462.

  • Kirby-Lee, K. A., Peer J., Preprints, 2017, 5, e3373v; https://doi.org/10.7287/peerj.preprints.3373v1.

  • Rangineni, J., Effect of Goldenseal (Hydrastis canadensis) on bacterial multi drug resistant efflux pumps, 2011.

  • Boone, L. Powerful Plant-Based Superfoods: The Best Way to Eat for Maximum Health, Energy, and Weight Loss, Fair Winds Press, MA, USA, 2013.

  • Ross, A. and Thomas, S., J. Altern. Complement. Med., 2010, 16, 3–12.


Abstract Views: 457

PDF Views: 127




  • Antibiotic Abuse:Post-Antibiotic Apocalypse, Superbugs and Superfoods

Abstract Views: 457  |  PDF Views: 127

Authors

Renu Bisht
Chemical Biology Group, South Asian University, New Delhi 110 021, India
Priti Saxena
Chemical Biology Group, South Asian University, New Delhi 110 021, India

Abstract


Cases of antibiotic abuse have reached a phenomenal level worldwide and become a global health concern affecting a larger number of people than those affected by the disease itself. Facilitating generation of multidrug- resistant superbugs, antibiotic misuse practices are a pressing issue worldwide, with the threat to developing South Asian countries like India, being insurmountable. This commentary summarizes our knowledge about this global pandemic; its causes, effects and severity, and discusses the preventive measures taken to curb antibiotic abuse. We highlight emergence of superfoods as natural antibiotics (or alternative medicine) that hold potential to change the face of modern therapeutics.

References





DOI: https://doi.org/10.18520/cs%2Fv116%2Fi7%2F1055-1056