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Incidence of Fluorosis and Urinary Fluoride Concentration are not Always Positively Correlated with Drinking Water Fluoride Level


Affiliations
1 Department of Zoology, Pearson Memorial Hospital, Visva-Bharati, Santiniketan 731 235, India
2 Pearson Memorial Hospital, Visva-Bharati, Santiniketan 731 235, India
 

The aim of this study was to assess the effect of fluoride on human health, focusing on the incidence of fluorosis, urinary fluoride concentration and fluoride level in drinking water in three fluoride-affected villages of Birbhum district, West Bengal, India. In one village urinary fluoride concentration was very high along with the occurrence of severe dental and skeletal fluorosis, though fluoride level in drinking water was within the permissible limit. The present study suggests that fluoride intake through other sources is also an important contributing factor in fluorosis, corroborating previous reports on high fluoride contents in crops and vegetables grown in fluoride-affected areas.

Keywords

Dental And Skeletal Fluorosis, Drinking Water, Fluoride Level, Urinary Fluoride Concentration.
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  • Hem, J. D., Study and Interpretation of the Chemical Characteristic of Natural Water, Department of the Interior, US Geological Survey, USA, 1985, vol. 2254.

  • Handa, B. K., Geochemistry and genesis of fluoride-containing ground waters in India. Ground Water, 1975, 13(3), 275–281.

  • Cronin, S. J. and Sharp, D. S., Environmental impacts on health from continuous volcanic activity at Yasur (Tanna) and Ambrym, Vanuatu. Int. J. Environ. Health Res., 2002, 12(2), 109–123.

  • Ramanaiah, S. V., Mohan, S. V., Rajkumar, B. and Sarma, P. N., Monitoring of fluoride concentration in ground water of Prakasham district in India: correlation with physico-chemical parameters. J. Environ. Sci. Eng., 2006, 48(2), 129–134.

  • Datta, P., Deb, D. and Tyagi, S., Stable isotope (18O) investigations on the processes controlling fluoride contamination of groundwater. J. Contam. Hydrol., 1996, 24(1), 85–96.

  • Patra, R., Dwivedi, S., Bhardwaj, B. and Swarup, D., Industrial fluorosis in cattle and buffalo around Udaipur, India. Sci. Total Environ., 2000, 253(1–3), 145–150.

  • Rao, N. S., The occurrence and behaviour of fluoride in the groundwater of the Lower Vamsadhara River basin, India. Hydrol. Sci. J., 1997, 42(6), 877–892.

  • World Health Organization, Guidelines for Drinking-Water Quality: Recommendations, WHO, Geneva, 2004, vol. 1.

  • Czarnowski, W., Wrzeniowska, K. and Krechniak, J., Fluoride in drinking water and human urine in Northern and Central Poland. Sci. Total Environ., 1996, 191(1–2), 177–184.

  • Whitford, G. M., Intake and metabolism of fluoride. Adv. Dent. Res., 1994, 8(1), 5–14.

  • Dean, H. T., The investigation of physiological effects by the epidemiological method. Fluoride Dent. Health, 1942, 23–31.

  • Fejerskov, O., Manji, F. and Baelum, V., The nature and mechanisms of dental fluorosis in man. J. Dent. Res., 1990, 69(2), 692– 700.

  • Boivin, G., Chavassieux, P., Chapuy, M., Baud, C. and Meunier, P., Skeletal fluorosis: histomorphometric analysis of bone changes and bone fluoride content in 29 patients. Bone, 1989, 10(2), 89–99.

  • World Health Organization, Fluorine and Fluorides, WHO, Geneva, 1984.

  • Mullenix, P. J., Denbesten, P. K., Schunior, A. and Kernan, W. J., Neurotoxicity of sodium fluoride in rats. Neurotoxicol. Teratol., 1995, 17(2), 169–177.

  • Trivedi, N., Mithal, A., Gupta, S. K. and Godbole, M. M., Reversible impairment of glucose tolerance in patients with endemic fluorosis. Diabetologia, 1993, 36(9), 826–828.

  • Chattopadhyay, A., Podder, S., Agarwal, S. and Bhattacharya, S., Fluoride-induced histopathology and synthesis of stress protein in liver and kidney of mice. Arch. Toxicol., 2010, 85(4), 327–335.

  • Podder, S., Chattopadhyay, A., Bhattacharya, S. and Ray, M. R., Differential in vivo genotoxic effects of lower and higher concentrations of fluoride in mouse bone marrow cells. Fluoride, 2008, 41(4), 301–307.

  • Podder, S., Chattopadhyay, A., Bhattacharya, S. and Ranjan, R. M., Histopathology and cell cycle alteration in the spleen of mice from low and high doses of sodium fluoride. Fluoride, 2010, 43(4), 237–245.

  • Mukhopadhyay, D., Priya, P. and Chattopadhyay, A., Sodium fluoride affects zebrafish behaviour and alters mRNA expressions of biomarker genes in the brain: role of Nrf2/Keap1. Environ. Toxicol. Pharmacol., 2015, 40(2), 352–359.

  • Cerklewski, F. L., Fluoride bioavailability – nutritional and clinical aspects. Nutr. Res., 1997, 17(5), 907–929.

  • Zober, A., Mallinckrodt, M. G. and Schaller, K. H., Renal fluoride excretion as a useful parameter for monitoring hydrofluoric acidexposed persons. Int. Arch. Occup. Environ. Health, 1977, 40(1), 13–24.

  • Rum, G., Lee, W. Y. and Gardea-Torresdey, J., Applications of a US EPA-approved method for fluoride determination in an environmental chemistry laboratory: fluoride detection in drinking water. J. Chem. Educ., 2000, 77(12), 1604.

  • Mukhopadhyay, D. and Chattopadhyay, A., Induction of oxidative stress and related transcriptional effects of sodium fluoride in female zebrafish liver. Bull. Environ. Contam. Toxicol., 2014, 93(1), 64–70.

  • Eller, P. M., NIOSH Manual of Analytical Methods (vol. 94), Diane Publishing, 1994.

  • Anasuya, A. and Paranjape, P. K., Effect of parboiling on fluoride content of rice. Fluoride, 1996, 29(4), 193–201.

  • Tegegne, B., Chandravanshi, B. S. and Zewge, F., Fluoride levels in commercially available rice in Ethiopia. Bull. Chem. Soc. Ethiop., 2013, 27(2), 179–189.

  • Arora, G. and Bhateja, S., Estimating the fluoride concentration in soil and crops grown over it in and around Mathura, Uttar Pradesh, India. Am. J. Ethnomed., 2014, 1(1), 36–41.


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  • Incidence of Fluorosis and Urinary Fluoride Concentration are not Always Positively Correlated with Drinking Water Fluoride Level

Abstract Views: 369  |  PDF Views: 137

Authors

Arpan Dey Bhowmik
Department of Zoology, Pearson Memorial Hospital, Visva-Bharati, Santiniketan 731 235, India
Pallab Shaw
Department of Zoology, Pearson Memorial Hospital, Visva-Bharati, Santiniketan 731 235, India
Paritosh Mondal
Department of Zoology, Pearson Memorial Hospital, Visva-Bharati, Santiniketan 731 235, India
Chayan Munshi
Department of Zoology, Pearson Memorial Hospital, Visva-Bharati, Santiniketan 731 235, India
Swarnak Chatterjee
Pearson Memorial Hospital, Visva-Bharati, Santiniketan 731 235, India
Shelley Bhattacharya
Department of Zoology, Pearson Memorial Hospital, Visva-Bharati, Santiniketan 731 235, India
Ansuman Chattopadhyay
Department of Zoology, Pearson Memorial Hospital, Visva-Bharati, Santiniketan 731 235, India

Abstract


The aim of this study was to assess the effect of fluoride on human health, focusing on the incidence of fluorosis, urinary fluoride concentration and fluoride level in drinking water in three fluoride-affected villages of Birbhum district, West Bengal, India. In one village urinary fluoride concentration was very high along with the occurrence of severe dental and skeletal fluorosis, though fluoride level in drinking water was within the permissible limit. The present study suggests that fluoride intake through other sources is also an important contributing factor in fluorosis, corroborating previous reports on high fluoride contents in crops and vegetables grown in fluoride-affected areas.

Keywords


Dental And Skeletal Fluorosis, Drinking Water, Fluoride Level, Urinary Fluoride Concentration.

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DOI: https://doi.org/10.18520/cs%2Fv116%2Fi9%2F1551-1554