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Mtb-HID:A Unified Database of Host–Pathogen Interaction for Various Mycobacterium tuberculosis Strains


Affiliations
1 Department of Biotechnology, Graphic Era Deemed to be University, Dehradun 248 002, India
 

Databases developed till now for studying human– Mycobacterium tuberculosis (MTB) host–pathogen interactions are scarce and pertain to specific strains of pathogen. Therefore, in the present study, a database (Mtb-HID) has been developed to serve as a unified host–pathogen interaction platform with information on interaction between various strains of MTB and humans. Mtb-HID is different from other databases since it houses information about multiple strains and is an extensive integrated repository of experimental host–pathogen protein–protein interaction (HP-PPIs) data imported from various public databases and derived from interolog-based HP-PPIs. Currently, Mtb-HID hosts records of interaction between five MTB strains and human host. It is freely accessible at http://www.pantlab.co.in/mtb-hid/.

Keywords

Database, Host–Pathogen Interaction, Humans, Mycobacterium tuberculosis.
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  • Mtb-HID:A Unified Database of Host–Pathogen Interaction for Various Mycobacterium tuberculosis Strains

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Authors

Kumud Pant
Department of Biotechnology, Graphic Era Deemed to be University, Dehradun 248 002, India
Devvret
Department of Biotechnology, Graphic Era Deemed to be University, Dehradun 248 002, India
Neema Tufchi
Department of Biotechnology, Graphic Era Deemed to be University, Dehradun 248 002, India
Ajay Pandaya
Department of Biotechnology, Graphic Era Deemed to be University, Dehradun 248 002, India
Ashish Thapliyal
Department of Biotechnology, Graphic Era Deemed to be University, Dehradun 248 002, India

Abstract


Databases developed till now for studying human– Mycobacterium tuberculosis (MTB) host–pathogen interactions are scarce and pertain to specific strains of pathogen. Therefore, in the present study, a database (Mtb-HID) has been developed to serve as a unified host–pathogen interaction platform with information on interaction between various strains of MTB and humans. Mtb-HID is different from other databases since it houses information about multiple strains and is an extensive integrated repository of experimental host–pathogen protein–protein interaction (HP-PPIs) data imported from various public databases and derived from interolog-based HP-PPIs. Currently, Mtb-HID hosts records of interaction between five MTB strains and human host. It is freely accessible at http://www.pantlab.co.in/mtb-hid/.

Keywords


Database, Host–Pathogen Interaction, Humans, Mycobacterium tuberculosis.

References





DOI: https://doi.org/10.18520/cs%2Fv118%2Fi2%2F292-297