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X-ray crystal structure of a new triterpene, 3,23-cycloglutin-5(10)-ene from Euphorbia vajravelui


Affiliations
1 Phytochemistry and Phytopharmacology Division, KSCSTE-Jawaharlal Nehru Tropical Botanic Garden and Research Institute, Pacha-Palode, Thiruvananthapuram 695 562, India
 

Euphorbia species are known for their diversity of terpenoid constituents. Euphorbia vajravelui is an endemic plant species distributed in the southern Western Ghats of India. Though conventional spectroscopic techniques are common in structure elucidation of secondary metabolites from plants, X-ray crystal structure analysis of a compound offers valuable information with minimum sample requirement. The present study reports the characterization of a new triterpene, 3,23-cycloglutin-5(10)-ene isolated from E. vajravelui, using single-crystal X-ray diffraction studies. Triclinic crystalline system was obtained for the compound, having P1 space group with unit cell parameters; a = 6.2907(8) Å, b = 7.4458(10) Å, c = 14.5802(18) Å, α = 94.899(6)°, β = 95.365(6)°, γ = 114.392(6)°, V = 613.43(14) Å3 and Z = 1. The triterpene has a glutinane skeletal structure containing a cyclopropane ring with a methyl group.

Keywords

Euphorbia vajravelui, glutinane skeleton, terpenoid constituents, triterpene, X-ray crystal structure.
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  • X-ray crystal structure of a new triterpene, 3,23-cycloglutin-5(10)-ene from Euphorbia vajravelui

Abstract Views: 417  |  PDF Views: 116

Authors

Vijayalekshmi Anju
Phytochemistry and Phytopharmacology Division, KSCSTE-Jawaharlal Nehru Tropical Botanic Garden and Research Institute, Pacha-Palode, Thiruvananthapuram 695 562, India
Koranappallil Bahuleyan Rameshkumar
Phytochemistry and Phytopharmacology Division, KSCSTE-Jawaharlal Nehru Tropical Botanic Garden and Research Institute, Pacha-Palode, Thiruvananthapuram 695 562, India

Abstract


Euphorbia species are known for their diversity of terpenoid constituents. Euphorbia vajravelui is an endemic plant species distributed in the southern Western Ghats of India. Though conventional spectroscopic techniques are common in structure elucidation of secondary metabolites from plants, X-ray crystal structure analysis of a compound offers valuable information with minimum sample requirement. The present study reports the characterization of a new triterpene, 3,23-cycloglutin-5(10)-ene isolated from E. vajravelui, using single-crystal X-ray diffraction studies. Triclinic crystalline system was obtained for the compound, having P1 space group with unit cell parameters; a = 6.2907(8) Å, b = 7.4458(10) Å, c = 14.5802(18) Å, α = 94.899(6)°, β = 95.365(6)°, γ = 114.392(6)°, V = 613.43(14) Å3 and Z = 1. The triterpene has a glutinane skeletal structure containing a cyclopropane ring with a methyl group.

Keywords


Euphorbia vajravelui, glutinane skeleton, terpenoid constituents, triterpene, X-ray crystal structure.

References





DOI: https://doi.org/10.18520/cs%2Fv120%2Fi10%2F1623-1626