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National Innovation System for Crispr Genome Editing Research in India: An Empirical Analysis


Affiliations
1 Plaksha University, Mohali 140 306, India
2 DST-Centre for Policy Research, Indian Institute of Science, Bengaluru 560 012, India

The clustered regularly interspaced short palindromic repeats (CRISPR)-Cas genome editing technology holds great potential in advancing the fields of healthcare, agriculture, and basic biology research. This study uses the national innovation system framework to identify key actors in India’s CRISPR research landscape and their roles in technology development and diffusion. Bibliographic analysis revealed that almost half of Indian CRISPR research publications are review articles or book chapters. Patentscope analysis showed that only 13.7% of CRISPR-related patent applications are attributed to Indian nationals, indicating international dominance. The Indian CRISPR research ecosystem is primarily supported by the Department of Biotechnology, Government of India. Addressing lack of hands-on learning opportunities, minimal collaboration amongst limited researchers, and absence of dedicated institutes of excellence are crucial to accelerate CRISPR technology innovation in India. We believe these inferences can be extrapolated to other developing countries that spend a similar percentage of their gross domestic product on biotechnology research.

Keywords

CRISPR research and development, CRISPR research in India, Department of Biotechnology, emerging national innovation systems, innovation system challenges.
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  • National Innovation System for Crispr Genome Editing Research in India: An Empirical Analysis

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Authors

Avishi Rajgharhia
Plaksha University, Mohali 140 306, India
N. Nandana
Plaksha University, Mohali 140 306, India
Prachi Parakh
Plaksha University, Mohali 140 306, India
Sarthak Sachdev
Plaksha University, Mohali 140 306, India
Tanya Sravan
Plaksha University, Mohali 140 306, India
Nidhi Singh
DST-Centre for Policy Research, Indian Institute of Science, Bengaluru 560 012, India
Navjot Kaur
Plaksha University, Mohali 140 306, India

Abstract


The clustered regularly interspaced short palindromic repeats (CRISPR)-Cas genome editing technology holds great potential in advancing the fields of healthcare, agriculture, and basic biology research. This study uses the national innovation system framework to identify key actors in India’s CRISPR research landscape and their roles in technology development and diffusion. Bibliographic analysis revealed that almost half of Indian CRISPR research publications are review articles or book chapters. Patentscope analysis showed that only 13.7% of CRISPR-related patent applications are attributed to Indian nationals, indicating international dominance. The Indian CRISPR research ecosystem is primarily supported by the Department of Biotechnology, Government of India. Addressing lack of hands-on learning opportunities, minimal collaboration amongst limited researchers, and absence of dedicated institutes of excellence are crucial to accelerate CRISPR technology innovation in India. We believe these inferences can be extrapolated to other developing countries that spend a similar percentage of their gross domestic product on biotechnology research.

Keywords


CRISPR research and development, CRISPR research in India, Department of Biotechnology, emerging national innovation systems, innovation system challenges.



DOI: https://doi.org/10.18520/cs%2Fv127%2Fi6%2F674-683