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Toxicity Study in Mice Fed with Corn Produced in Soil Containing Tannery Sludge Vermicompost and Irrigated with Domestic Wastewater


Affiliations
1 Laboratorio de Pesquisas Biologicas, Instituto Federal Goiano – Campus Urutai, GO, Brazil
2 Programa de Pos-Graduacao em Biodiversidade Animal, Universidade Federal de Goias – Campus Samambaia, GO, Brazil
3 Laboratorio de Genetica e Biologia Molecular, Instituto Federal Goiano – Campus Urutai, GO, Brazil
 

Growing food in unconventional systems such as those using irrigation with domestic wastewater and the use of potentially toxic waste has generated resistance from producers and consumers. Here, we evaluate the possible physical and biochemical damage to Swiss mice fed for 13 weeks with corn produced in soil containing tannery sludge vermicompost and irrigated with wastewater from domestic sewage. The corn was offered as an additional food to standard rodent chow at a daily concentration of 15 g/kg of body mass. The results showed no changes in body weight of the animals during the experimental period. The consumption of grain and weight gain of the animals was stable. The total protein, albumin, globulin and alkaline phosphatase levels did not differ among experimental groups. In addition, macroscopic analysis of the liver of the animals showed no sign of injury or disorders. Thus, we preliminarily conclude that the maize produced in this way is innocuous to animals. However, further studies are needed to evaluate other variables not measured in the present study which can contribute to food security and the nutrition of the corn thus produced.

Keywords

Agro-industrial Waste, Animal Models, Toxicity, Wastewater.
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  • Toxicity Study in Mice Fed with Corn Produced in Soil Containing Tannery Sludge Vermicompost and Irrigated with Domestic Wastewater

Abstract Views: 324  |  PDF Views: 119

Authors

Guilherme Malafaia
Laboratorio de Pesquisas Biologicas, Instituto Federal Goiano – Campus Urutai, GO, Brazil
Dieferson da Costa Estrela
Programa de Pos-Graduacao em Biodiversidade Animal, Universidade Federal de Goias – Campus Samambaia, GO, Brazil
Wellington Alves Mizael da Silva
Laboratorio de Pesquisas Biologicas, Instituto Federal Goiano – Campus Urutai, GO, Brazil
Abraao Tiago Batista Guimaraes
Laboratorio de Pesquisas Biologicas, Instituto Federal Goiano – Campus Urutai, GO, Brazil
Bruna de Oliveira Mendes
Laboratorio de Pesquisas Biologicas, Instituto Federal Goiano – Campus Urutai, GO, Brazil
Aline Sueli de Lima Rodrigues
Laboratorio de Pesquisas Biologicas, Instituto Federal Goiano – Campus Urutai, GO, Brazil
Ivandilson Pessoa Pinto de Menezes
Laboratorio de Genetica e Biologia Molecular, Instituto Federal Goiano – Campus Urutai, GO, Brazil

Abstract


Growing food in unconventional systems such as those using irrigation with domestic wastewater and the use of potentially toxic waste has generated resistance from producers and consumers. Here, we evaluate the possible physical and biochemical damage to Swiss mice fed for 13 weeks with corn produced in soil containing tannery sludge vermicompost and irrigated with wastewater from domestic sewage. The corn was offered as an additional food to standard rodent chow at a daily concentration of 15 g/kg of body mass. The results showed no changes in body weight of the animals during the experimental period. The consumption of grain and weight gain of the animals was stable. The total protein, albumin, globulin and alkaline phosphatase levels did not differ among experimental groups. In addition, macroscopic analysis of the liver of the animals showed no sign of injury or disorders. Thus, we preliminarily conclude that the maize produced in this way is innocuous to animals. However, further studies are needed to evaluate other variables not measured in the present study which can contribute to food security and the nutrition of the corn thus produced.

Keywords


Agro-industrial Waste, Animal Models, Toxicity, Wastewater.



DOI: https://doi.org/10.18520/cs%2Fv109%2Fi7%2F1326-1332