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Biocompatibility Studies of Electron Beam Cured Pressure Sensitive Adhesive Tape for Medical Application


Affiliations
1 Shriram Institute for Industrial Research, 19-University Road, Delhi 110 007, India
2 Vinoba Bhave University, Hazaribag, Jharkhand 825 301, India
 

Polyurethane (PU)-based pressure-sensitive adhesive (PSA) tapes are commonly used during surgery. Such devices made for biomedical applications must be biocompatible and biologically safe while in use in the human body as their ingredients may leach off of a device into an adjacent tissue and can harm the body during or after application. In the present study, various methods required for biocompatibility establishment, e.g. cytotoxicity, irritation and sensitization for a device, have been analysed and presented following suitable specifications. The study also emphasizes on the developmental and curing mechanism of biomedical adhesive tape by electron beam (e-beam) irradiation.
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  • Biocompatibility Studies of Electron Beam Cured Pressure Sensitive Adhesive Tape for Medical Application

Abstract Views: 287  |  PDF Views: 101

Authors

Anil Kumar Singh
Shriram Institute for Industrial Research, 19-University Road, Delhi 110 007, India
Gurdeep Singh
Vinoba Bhave University, Hazaribag, Jharkhand 825 301, India

Abstract


Polyurethane (PU)-based pressure-sensitive adhesive (PSA) tapes are commonly used during surgery. Such devices made for biomedical applications must be biocompatible and biologically safe while in use in the human body as their ingredients may leach off of a device into an adjacent tissue and can harm the body during or after application. In the present study, various methods required for biocompatibility establishment, e.g. cytotoxicity, irritation and sensitization for a device, have been analysed and presented following suitable specifications. The study also emphasizes on the developmental and curing mechanism of biomedical adhesive tape by electron beam (e-beam) irradiation.

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DOI: https://doi.org/10.18520/cs%2Fv110%2Fi6%2F1023-1030