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Unnikrishnan, B. S.
- Biogenic Silver Nanoparticles Embedded Polyvinyl Alcohol Nanofibrous Scaffolds Avert Tumour and Bacterial Growth
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Authors
Affiliations
1 Laboratory of Biopharmaceuticals and Nanomedicine, Division of Cancer Research, Regional Cancer Centre, Thiruvananthapuram 695 019, IN
2 Chemical Sciences and Technology Division, Organic Chemistry Section, CSIR-National Institute for Interdisciplinary Science and Technology, Thiruvananthapuram 695 019, IN
1 Laboratory of Biopharmaceuticals and Nanomedicine, Division of Cancer Research, Regional Cancer Centre, Thiruvananthapuram 695 019, IN
2 Chemical Sciences and Technology Division, Organic Chemistry Section, CSIR-National Institute for Interdisciplinary Science and Technology, Thiruvananthapuram 695 019, IN
Source
Current Science, Vol 116, No 10 (2019), Pagination: 1735-1741Abstract
This communication describes a carefully designed strategy which blends biogenic silver nanoparticles with PVA scaffolds to fabricate SNP@PVA electrospun scaffolds with admirable physico-chemical properties. The hybrid scaffold demonstrated cyto-compatibility and hemo-compatibility with no adverse effects on the surrounding cells, as demonstrated by multiple assays. The growth of cancer cells was greatly prevented by SNP@PVA scaffolds, while allowing growth of normal cells. The outstanding antimicrobial features of the scaffold can be attributed to the presence of silver na-noparticles and proves the use of SNP@PVA for bio-medical applications.Keywords
Cancer Cells, Electrospinning, Nanofibrous Scaffold, Polyvinyl Alcohol, Silver Nanoparticles.Full Text
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