Image Registration in Digital Ophthalmic Images for Variation of the Pattern Shift VEP with the Effect of Rate of Stimulation

It is important to check the variability of a number of parameter for reliable interpretation of transient PSVEP. The pattern reversal frequency if increased from 1 Hz to 4 Hz, the P-100 latency increase by 4.8 m sec. At a faster rate, the waveforms become less distinct and stimulation above 8-10 Hz result in a steady state VEP. This work presents a technique for a reliable extraction P-100 latency and amplitude using a SVD algorithm. The challenge of image registration (the process of correctly aligning two or more images accounting for all possible source of distortion) is of general interest in image processing. This research focused on investigating potential registration algorithms for transforming partially overlapping images which have only a partially over lapping images of the retina into a single overlapping composite image to aid physicians in assessment of retinal health, and on registering vectors from known common points in the images to be registered. All potential transforms between images are generated, with the correct registration producing a tight cluster of data points in the space of transform coefficients. This registration can be carried out for images of the same subject taken at different times, images taken under different modalities, and images which have only a partial overlap area.