The Effects and Comparison in Treatment Approaches of Matrix, Methadone, Buprenorphine, Matrix with Buprenorphine and Matrix with Methadone in Methaphetamine Dependent Patients

This undergoing study is considering effects and comparison in treatment approaches of matrix; methadone, buprenorphine; matrix with buprenorphine and matrix with methadone in methamphetamine dependent patients. The sample consisted of 36 methaphetamine dependent patients, who referred to addiction treatment centers of Isfahan were selected, and classified randomly, into six groups of treatment: First: Matrix treatments, Second: Methadone drug, Third: Bupernorphine drug, Fourth: Receiving methadone treatment combined with matrix treatment, Fifth: Receiving Buprenorphine treatment combined with matrix treatment, Sixth: Control group (placebo). Frequent urine test has been taking from those patients, after collecting data, obtained data is used to compare groups and analyze the results. Descriptive (frequencies, averages and percent cumulative) and inferential method (chi-square) has been used in SPSS as a statistical method to analyze the data. The result revealed that Matrix treatment with Buprenorphine for the first phase of treatment demonstrated positive outcomes, but after 2 months of leaving the slip rate is greatly increased. Matrix treatment alone for beginning of the treatment in comparison with matrix treatment with Buprenorphine had not good results, But the continued and sustained participation of the patients in the sessions of matrix ships are severely reduced and results were better than treatment of Buprenorphine with matrix. Methadone and Buprenorphine treatment alone were also completely ineffective.