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Electre Methods in Solving Group Decision Support System Bioinformatics on Gene Mutation Detection Simulation


Affiliations
1 Department of Information System, Computer Science Faculty of Sriwijaya University, Indonesia
2 Departement of Computer Science and Electronics, Gadjah Mada University, Indonesia
 

Analysis of genes expression can be done with the investigation of a particular microarray data for the description of a gen. This is done to identify what genes that were active in the human body. Detection of gene mutation is an activity that can provide contribution in the medical field. Detection of mutated gene is needed to avoid the diseases caused by them such as cancer. The detection of gene mutations can be performed by utilizing computer-based system. Group Decision Support System (GDSS) is a computer-based system that can be utilized in detecting human gene mutations that cause disease. The ELECTRE method, which is a Multi-Attribute Decision Making, is a method in modeling multi-criteria GDSS. In this paper we propose implementation of model for multi-criteria GDSS in which the simulation data is the mutated genes that can cause cancer.

Keywords

Bioinformatics, Group Decision Support System, ELECTRE, Gene Mutation.
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  • Electre Methods in Solving Group Decision Support System Bioinformatics on Gene Mutation Detection Simulation

Abstract Views: 529  |  PDF Views: 232

Authors

Ermatita
Department of Information System, Computer Science Faculty of Sriwijaya University, Indonesia
Sri Hartati
Departement of Computer Science and Electronics, Gadjah Mada University, Indonesia
Retantyo Wardoyo
Departement of Computer Science and Electronics, Gadjah Mada University, Indonesia
Agus Harjoko
Departement of Computer Science and Electronics, Gadjah Mada University, Indonesia

Abstract


Analysis of genes expression can be done with the investigation of a particular microarray data for the description of a gen. This is done to identify what genes that were active in the human body. Detection of gene mutation is an activity that can provide contribution in the medical field. Detection of mutated gene is needed to avoid the diseases caused by them such as cancer. The detection of gene mutations can be performed by utilizing computer-based system. Group Decision Support System (GDSS) is a computer-based system that can be utilized in detecting human gene mutations that cause disease. The ELECTRE method, which is a Multi-Attribute Decision Making, is a method in modeling multi-criteria GDSS. In this paper we propose implementation of model for multi-criteria GDSS in which the simulation data is the mutated genes that can cause cancer.

Keywords


Bioinformatics, Group Decision Support System, ELECTRE, Gene Mutation.