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Study of Vitamin-D Status in Patients with Low Backache


Affiliations
1 Department of Neurology, Gauhati Medical College & Hospital, Guwahati, Assam, India
2 Department of Biochemistry, Gauhati Medical College & Hospital, Guwahati, Assam, India
3 Department of Anesthesiology, Gauhati Medical College & Hospital, Guwahati, Assam, India
 

Introduction: Apart from its established role in calcium homeostasis, studies have found vitamin D to be very much important for the normal maintenance and functioning of the muscles and nerves. Aims: i) To study the vitamin D levels in patients of low back ache ii) compare it with a control population. Methods: The study was designed as a case control study, with 100 cases and 100 controls. Patients with complaint of low backache were included in the study. A sample of venous blood was collected for vitamin D estimation. Results: In this study mean vitamin D level in the case group was found to be 29.19 ng/ml and in the control group 38.45ng/ml. P-value was found to be <.0001. Vitamin D deficiency and insufficiency was found more in females than males in both groups. 77.5% of the female patients and 45% of male patients had below normal vitamin D levels. Conclusion: There is a high possibility that vitamin D deficiency has a role to play in the aetiology of low backache.

Keywords

Hypovitaminosis D, Myopathy, Pro-Inflammatory, Skeletal, Supplementation.
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  • Study of Vitamin-D Status in Patients with Low Backache

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Authors

Papori Borah
Department of Neurology, Gauhati Medical College & Hospital, Guwahati, Assam, India
Firdushi Begum
Department of Biochemistry, Gauhati Medical College & Hospital, Guwahati, Assam, India
R. Khakhlari Arjun
Department of Anesthesiology, Gauhati Medical College & Hospital, Guwahati, Assam, India
K. Kayal Ashok
Department of Neurology, Gauhati Medical College & Hospital, Guwahati, Assam, India
Munindra Goswami
Department of Neurology, Gauhati Medical College & Hospital, Guwahati, Assam, India

Abstract


Introduction: Apart from its established role in calcium homeostasis, studies have found vitamin D to be very much important for the normal maintenance and functioning of the muscles and nerves. Aims: i) To study the vitamin D levels in patients of low back ache ii) compare it with a control population. Methods: The study was designed as a case control study, with 100 cases and 100 controls. Patients with complaint of low backache were included in the study. A sample of venous blood was collected for vitamin D estimation. Results: In this study mean vitamin D level in the case group was found to be 29.19 ng/ml and in the control group 38.45ng/ml. P-value was found to be <.0001. Vitamin D deficiency and insufficiency was found more in females than males in both groups. 77.5% of the female patients and 45% of male patients had below normal vitamin D levels. Conclusion: There is a high possibility that vitamin D deficiency has a role to play in the aetiology of low backache.

Keywords


Hypovitaminosis D, Myopathy, Pro-Inflammatory, Skeletal, Supplementation.

References