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Spindle Cell Liposarcoma:A Rare Variant of Liposarcoma Arising in Forearm with Ulceration
Liposarcoma is the most common soft tissue sarcoma accounting for 20% of all mesenchymal malignancies. Spindle cell liposarcoma is a rare histological variant of liposarcoma. Spindle Cell Liposarcoma presenting with ulceration is a rare entity in the history of literature. We report a case of spindle cell liposarcoma arising from the right forearm presenting with ulceration. A 14-yearold young boy presented with a slow growing ulcer over the right forearm. Histological examination of biopsy showed spindled and stellate shaped cells in a myxoid background and many curved vessels suggesting myxoid and round cell liposarcoma suggesting spindle cell liposarcoma. Based on this, a histological diagnosis of spindle cell liposarcoma was made. Spindle cell liposarcoma is a rare variant of well-differentiated liposarcoma characterized by prominent spindle cell component. In previously reported cases spindle cell liposarcoma was demonstrated in the subcutaneous tissues of limbs, trunk, shoulder girdle, buttock presenting a mass without ulceration. Main differential diagnoses include benign lesions such as spindle cell lipoma, diffuse neurofibroma as well as dermatofibrosarcoma protuberans and other malignancies such as sclerosingliposarcoma, myxofibrosarcoma, malignant peripheral nerve sheath tumor and fibromyxoid sarcoma. Spindle cell Liposarcomas tend to recur locally and may have a potential for metastasis. Wide excision and long term follow up looking for recurrence and metastasis is necessary. To our knowledge, Liposarcoma presenting with ulceration at forearm has not been observed in literature. So, our case is a rare variant of liposarcoma arising at forearm with ulceration.
Keywords
Spindle Cell Liposarcoma, Leg, Atypical Lipomatous Tumor, well Differentiated Liposarcomas, Spindle Cell.
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