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Studies on Copoly (N-Vinylpyrrolidone – Acrylic acid) – As an Antimicrobial


Affiliations
1 Department of Chemistry, Sri Siddhartha Institute of Technology, Tumkur, Karnataka, India
2 Sri Siddhartha Institute of Technology, Tumkur, Karnataka, India
3 Department of Chemistry, Govt. First Grade College, Koratagere, Tumkur, Karnataka, India
4 Department of Bio-Technology, Siddaganga Institute of Technology, Tumkur, Karnataka, India
 

Copolymer of N-vinylpyrrolidone (NVP) and Acrylic acid (AA) was prepared by using hydrogen peroxide as initiator in Tetrahydrofuran medium at 450C under inert atmosphere. The copolymer (B) prepared was made to react with N, N – Diethylaminoethanol (DEAE) to form an ester (EB) through acid group of acrylic acid. Synthesized copolymer and its graft were characterized by FTIR, H1NMR and C13NMR.  The antimicrobial property of these compounds was investigated by agar well diffusion method. Two grams +ve bacterial strains used were Bacillus pumillus – 1640 and Staphylococcus aureus – 3160, two grams –ve bacterial strains were Escherichia coli – 45 and Enterobacteraerogenes – 2822. The fungal strains used were Fusariumoxysporum – 2087 and Aspergillusniger – 4325.


Keywords

N-Vinylpyrrolidone, Acrylic Acid, FTIR, H1NMR, C13NMR, Anti-Microbial Activity.
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  • Studies on Copoly (N-Vinylpyrrolidone – Acrylic acid) – As an Antimicrobial

Abstract Views: 216  |  PDF Views: 7

Authors

P. Hemalatha
Department of Chemistry, Sri Siddhartha Institute of Technology, Tumkur, Karnataka, India
M. K. Veeraiah
Sri Siddhartha Institute of Technology, Tumkur, Karnataka, India
K. V. Anasuya
Department of Chemistry, Govt. First Grade College, Koratagere, Tumkur, Karnataka, India
Anupama C. Mousumi Das
Department of Bio-Technology, Siddaganga Institute of Technology, Tumkur, Karnataka, India

Abstract


Copolymer of N-vinylpyrrolidone (NVP) and Acrylic acid (AA) was prepared by using hydrogen peroxide as initiator in Tetrahydrofuran medium at 450C under inert atmosphere. The copolymer (B) prepared was made to react with N, N – Diethylaminoethanol (DEAE) to form an ester (EB) through acid group of acrylic acid. Synthesized copolymer and its graft were characterized by FTIR, H1NMR and C13NMR.  The antimicrobial property of these compounds was investigated by agar well diffusion method. Two grams +ve bacterial strains used were Bacillus pumillus – 1640 and Staphylococcus aureus – 3160, two grams –ve bacterial strains were Escherichia coli – 45 and Enterobacteraerogenes – 2822. The fungal strains used were Fusariumoxysporum – 2087 and Aspergillusniger – 4325.


Keywords


N-Vinylpyrrolidone, Acrylic Acid, FTIR, H1NMR, C13NMR, Anti-Microbial Activity.