International Journal of Innovative Research and Development

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Synthesis, Characterization and Biological Studies of Azobenzothiazole Dyes


Affiliations
1 Department of Studies and Research in Chemistry, School of Chemical Sciences, Kuvempu University, Jnana Sahyadri, Shankaraghatta, Karnataka, India
2 Department of Biochemistry, Kuvempu University, Jnana Sahyadri, Shankaraghatta, Karnataka, India
 

Series of azobenzothiazole dyes were synthesized by coupling reaction of 2-naphthol, 8-hydroxy quinoline and 2,6-diamino pyridine with diazotized 2-Amino-6-nitrobenzothiazole as diazo component. These dyes have been prepared in good yields, and were characterized by UV–Vis, FT-IR and 1H NMR spectroscopic techniques. The synthesized azobenzothiazole dyes were screened for biological activity. The results of these investigations revealed that the newly synthesized compounds are potent antimicrobial agents. All the synthesized compounds exhibit significant antimicrobial activity. 


Keywords

2-Amino-6-Nitrobenzothiazole, Azo Dyes, Biological Activity.
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  • Synthesis, Characterization and Biological Studies of Azobenzothiazole Dyes

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Authors

C. T. Keerthi Kumar
Department of Studies and Research in Chemistry, School of Chemical Sciences, Kuvempu University, Jnana Sahyadri, Shankaraghatta, Karnataka, India
J. Keshavayya
Department of Studies and Research in Chemistry, School of Chemical Sciences, Kuvempu University, Jnana Sahyadri, Shankaraghatta, Karnataka, India
B. N. Ravi
Department of Studies and Research in Chemistry, School of Chemical Sciences, Kuvempu University, Jnana Sahyadri, Shankaraghatta, Karnataka, India
Sameer R. Patil
Department of Biochemistry, Kuvempu University, Jnana Sahyadri, Shankaraghatta, Karnataka, India

Abstract


Series of azobenzothiazole dyes were synthesized by coupling reaction of 2-naphthol, 8-hydroxy quinoline and 2,6-diamino pyridine with diazotized 2-Amino-6-nitrobenzothiazole as diazo component. These dyes have been prepared in good yields, and were characterized by UV–Vis, FT-IR and 1H NMR spectroscopic techniques. The synthesized azobenzothiazole dyes were screened for biological activity. The results of these investigations revealed that the newly synthesized compounds are potent antimicrobial agents. All the synthesized compounds exhibit significant antimicrobial activity. 


Keywords


2-Amino-6-Nitrobenzothiazole, Azo Dyes, Biological Activity.