Antibiotic Sensitivity Pattern of Pseudomonas aeruginosa Strains Isolated from Various Clinical Specimens at Civil Hospital, Rajkot, Gujarat, India

Pseudomonas aeruginosa is one of the most common gram-negative microorganisms identified in the clinical specimens of hospital admitted patients. This was a retrospective study done among the patients attending P.D.V. Medical College Hospital, Rajkot during August 2011 to January 2012. A total 1500 samples were tested out of which 103 strains of P. aeruginosa were isolated. Some of the isolates were from males 54 (52.42%) while 49 (47.57%) from females. Majority of the patients 26 (25.3%) were aged between 20-29 years and least 3 (2.9%) were between 50-59 years. A significant proportion 50 (48.5%) of the patients were from Pus specimen followed by Sputum 31 (30%) and Urine 8 (7.7%). Three of the clinical specimens including pus, Sputum and urine comprised of 89 (84%) of the total samples. The bacteria isolated were identified by colony morphology, microscopy and relevant biochemical tests. Antimicrobial sensitivity pattern was tested using standard guidelines. Antobiotic susceptibility pattern shows that P. aeruginosa is highly sensitive to Meropenem (87.6%), Cefepime (78.6%), Piperacillin (77.6%), Amikacin (74.71%), Ciprcfloxacin (54.63%), Tobramycin (50.8%), Gentamicin (50%). The result of the study shows that Meropenem is the most effective drug against P. aeruginosa, followed by cefepime, Piperacillin and Amikacin.