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Segmentation and Classification of Cervical Cytology Images Using Morphological and Statistical Operations


Affiliations
1 Centre for Information Technology and Engineering, Manonmaniam Sundaranar University, India
2 Department of Computer Science and Engineering, Hindustan University, India
     

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Cervical cancer that is a disease, in which malignant (cancer) cells form in the tissues of the cervix, is one of the fourth leading causes of cancer death in female community worldwide. The cervical cancer can be prevented and/or cured if it is diagnosed in the pre-cancerous lesion stage or earlier. A common physical examination technique widely used in the screening is called Papanicolaou test or Pap test which is used to detect the abnormality of the cell. Due to intricacy of the cell nature, automating of this procedure is still a herculean task for the pathologist. This paper addresses solution for the challenges in terms of a simple and novel method to segment and classify the cervical cell automatically. The primary step of this procedure is pre-processing in which de-nosing, de-correlation operation and segregation of colour components are carried out, Then, two new techniques called Morphological and Statistical Edge based segmentation and Morphological and Statistical Region Based segmentation Techniques- put forward in this paper, and that are applied on the each component of image to segment the nuclei from cervical image. Finally, all segmented colour components are combined together to make a final segmentation result. After extracting the nuclei, the morphological features are extracted from the nuclei. The performance of two techniques mentioned above outperformed than standard segmentation techniques. Besides, Morphological and Statistical Edge based segmentation is outperformed than Morphological and Statistical Region based Segmentation. Finally, the nuclei are classified based on the morphological value. The segmentation accuracy is echoed in classification accuracy. The overall segmentation accuracy is 97%.

Keywords

Cervical Cancer Cell, PAP Smear Test, Segmentation, Classification, Morphological And Statistical Edge Based Segmentation, Morphological and Statistical Region Based Segmentation.
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  • Jemal A, Bray F, Center M.M, Ferlay J, Ward E and Forman D, “Global Cancer Statistics”, CA: A Cancer Journal for Clinicians, Vol. 61, No. 2, pp. 69-90, 2011.
  • Human Papilloma virus and Related Diseases Report India, March 20, 2015. Website: www.HPVcentere.net.
  • http://www.cervicalcanceraction.org/whynow/about.php
  • Dr. E.R. Naganathan, S. Anantha Sivaprakasam and V. Saravana Kumar, “Enhanced Colour Image Segmentation on Cervical Cytology Image”, Proceedings of the International Conference on Applied Mathematics and Theoretical Computer Science, pp. 215-218, 2013.
  • Anantha Sivaprakasam Sivaprakasam and Naganathan Ealai Rengasari, “Segmentation of Cervical Image Using Unsupervised Clustering Algortihms with L*u*v Color Transformation”, Asian Journal of Information Technology, Vol. 14, No. 4, pp. 147-153, 2015.
  • S. Anantha Sivaprakasam and Dr. E.R. Naganathan, “Automatic Cervical Image Segmentation using Arithmetic and Threshold Concept”, Australian Journal of Basic and Applied Sciences, Vol. 8, No. 18, pp. 283-287, 2014.
  • Susanta Mukhopadhyay and Bhabatosh Chanda, “Multiscale Morphological Segmentation of Gray-Scale Images”, IEEE Transactions on Image Processing, Vol. 12, No. 5, pp. 533-549, 2003.
  • Thanatip Chankong, Nipon Theera-Umpon and Sansanee, Auephanwiriyakul, “Automatic Cervical Cell Segmentation and Classification in Pap Smears”, Computer Methods and Programs in Biomedicine, Vol. 113, No. 2, pp. 539-556, 2014.
  • Asli Genctav, Selim Aksoy and Sevgen Onder, “Unsupervised Segmentation and Classification of Cervical Images”, Pattern Recognition, Vol. 45, No. 12, pp. 4151-4168, 2012.
  • Karthigai Lakshmi and K Krishnaveni, “Automated Extraction of Cytoplasm and Nuclei from Cervical Cytology Images by Fuzzy Thresholding and Active Contours”, International Journal of Computer Applications, Vol. 73, No. 15, pp. 26-30, 2013.
  • N.B. Byju, Vilayil K. Sujathan, Ptrix Malm and R. Rajesh Kumar, “A Fast and Reliable Approach to Cell Nuclei Segmentation in Pap Stained Cervical Smears”, CSI Transactions on ICT, Vol. 1, No. 4, pp. 309-315, 2013.
  • M. Mohideen Fatima alias Niraimathi and Dr. V. Seenivasagam, “A Hybrid Image Segmentation of Cervical Cells by Bi-group Enhancement and Scan Line Filling”, International Journal of Computer Science and Information Technology & Security, Vol. 2, No. 2, pp. 368-375, 2012.
  • Naveed Abbas and Dzylkifli Mohamad, “Automatic Color Nuclei Segmentation of Leukocytes for Acute Leukemia”, Research Journal of Applied Sciences, Engineering and Technology, Vol. 7, No. 14, pp. 2987-2993, 2014.
  • Marina E. Plissiti, Christophoros Nikou and Antonia Charchanti, “Combining Shape, Texture and Intensity Features for Cell Nuclei Extraction in Pap Smear Images”, Pattern Recognition Letters, Vol. 32, No. 6, pp. 838-853, 2011.
  • Edward R. Dougherty and Jaakko T. Astola, “An Introduction to Nonlinear Image Processing”, First Edition, Society of Photo-Optical Instrumentation Engineers, 1994.
  • Gasteratos, “Mathematical Morphology Operations and Structuring Elements”, In CVonline: On-Line Compendium of Computer Vision, R. Fisher(ed) Available: http://www.dai.ed.ac.uk/ CVonline/transf.htm, 2001.
  • Edward R. Dougherty and Jaakko T. Astola, “An Introduction to Nonlinear Image Processing”, SPIE Optical Engineering Press, 1994.
  • Jean Serra, “Image Analysis and Mathematical Morphology”, Academic Press Inc., 1983.
  • F. Ortiz, F. Torres, E. De Juan and N. Cuenca, “Colour Mathematical Morphology for Neural Image Analysis”, Real Time Imaging, Vol. 8, No. 6, pp. 455-465, 2002.
  • Rahmadwati, G. Naghdy, M. Ros and C. Todd, “Morphological Characteristics of Cervical Cells for Cervical Cancer Diagnosis”, Proceedings of the 2011 2nd International Congress on Computer Applications and Computational Science, Vol. 2, pp. 235-243, 2012.
  • Anil Z. Chitade, Dr. S.K. Katiyar, “Colour Based Image Segmentation Using K-Means Clustering”, International Journal of Engineering Science and Technology, Vol. 2, No. 10, pp. 5319-5325, 2010.
  • Rafael C. Gonalez, Richare E. Woods and Steven L. Eddins, “Morphological Reconstruction”, Digital Image Processing Using MATLAB, MATLAB Digest, Academic Edition, 2002.
  • E. Martin, “Pap-Smear Classification”, Master’s Thesis, Technical University of Denmark, DTU, 2003.
  • C. Demir and B. Yener, “Automated Cancer Diagnosis based on Histopathological Images: A Systematic Survey”, Computer Science Technical Reports, Vol. cs-05-09, 2005.

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  • Segmentation and Classification of Cervical Cytology Images Using Morphological and Statistical Operations

Abstract Views: 291  |  PDF Views: 3

Authors

S. Anantha Sivaprakasam
Centre for Information Technology and Engineering, Manonmaniam Sundaranar University, India
E. R. Naganathan
Department of Computer Science and Engineering, Hindustan University, India

Abstract


Cervical cancer that is a disease, in which malignant (cancer) cells form in the tissues of the cervix, is one of the fourth leading causes of cancer death in female community worldwide. The cervical cancer can be prevented and/or cured if it is diagnosed in the pre-cancerous lesion stage or earlier. A common physical examination technique widely used in the screening is called Papanicolaou test or Pap test which is used to detect the abnormality of the cell. Due to intricacy of the cell nature, automating of this procedure is still a herculean task for the pathologist. This paper addresses solution for the challenges in terms of a simple and novel method to segment and classify the cervical cell automatically. The primary step of this procedure is pre-processing in which de-nosing, de-correlation operation and segregation of colour components are carried out, Then, two new techniques called Morphological and Statistical Edge based segmentation and Morphological and Statistical Region Based segmentation Techniques- put forward in this paper, and that are applied on the each component of image to segment the nuclei from cervical image. Finally, all segmented colour components are combined together to make a final segmentation result. After extracting the nuclei, the morphological features are extracted from the nuclei. The performance of two techniques mentioned above outperformed than standard segmentation techniques. Besides, Morphological and Statistical Edge based segmentation is outperformed than Morphological and Statistical Region based Segmentation. Finally, the nuclei are classified based on the morphological value. The segmentation accuracy is echoed in classification accuracy. The overall segmentation accuracy is 97%.

Keywords


Cervical Cancer Cell, PAP Smear Test, Segmentation, Classification, Morphological And Statistical Edge Based Segmentation, Morphological and Statistical Region Based Segmentation.

References