The Indian Practitioner

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Role of Trimetazidine in Preventing Myocardial Injury in Patients Undergoing Off Pump CABG


Affiliations
1 Mch CTVS, Assistant Professor, Era Medical College, India
2 KGMU Cardiology, Lucknow, India
3 Batra Hospital & Medical Research Center, New Delhi, India
     

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  • Saha KK.Off-pump coronary bypass grafting: the new gold standard. Indian J Thoracic Cardiovasc Surg.2018;34:3–5.

  • Hoffman JW Jr, et al. Myocardial reperfusion injury: etiology, mechanisms, and therapies. J Extra Corpor Technol. 2004;36:391-411.

  • Zhang N, Lei J, Liu Q, Huang W, Xiao H, Lei H. The effectiveness of preoperative trimetazidine on myocardial preservation in coronary artery bypass graft patients: a systematic review and meta-analysis. Cardiology. 2015;131:86-96.

  • Kantor PF, Lucien A, Kozak R, Lopaschuk GD. The antianginal drug trimetazidine shifts cardiac energy metabolism from fatty acid oxidation to glucose oxidation by inhibiting mitochondrial long-chain 3-ketoacyl coenzyme - A thiolase. Circ Res. 2000;86(5):580-88.

  • Turk T, Ata Y, Ufuk A, Hasan A, Kagan A, Senol Y. Efficacy of preoperative trimetazidine for preventing myocardial injury in patients undergoing off-pump coronary artery bypass grafting. Eur Res J. 2016;2:107-111.22222


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  • Role of Trimetazidine in Preventing Myocardial Injury in Patients Undergoing Off Pump CABG

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Authors

Khalid Iqbal
Mch CTVS, Assistant Professor, Era Medical College, India
Irshad Wani
KGMU Cardiology, Lucknow, India
Bashir Amhad
Batra Hospital & Medical Research Center, New Delhi, India

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