Bacteriological Study of Ocular Fluids in Endophthalmitis in a Tertiary Care Hospital
Subscribe/Renew Journal
Background and Aims: Endophthalmitis is the most challenging complication seen in ophthalmic practice. Endophthalmitis is defined as an inflammation of the inner structures of the eyeball i.e. uveal tissue and retina associated with the pouring of exudates in the vitreous cavity, anterior chamber, and posterior chamber. The study’s objective is to isolate and identify the bacteria causing endophthalmitis.
Materials and methods: It includes all case samples of vitreous tap and aqueous tap who underwent cataract surgery and cases of trauma to the eye in MINTO regional hospital. This study was carried out in the Post Graduate Research Laboratory, Department of Microbiology, Bangalore Medical College, Bangalore from December 2019 to August 2021.
Results: Forty cases of clinically diagnosed Endophthalmitis were studied, 14 (35%) of these cases were post-traumatic with which the majority of cases showed Staphylococcus epidermidis followed by Staphylococcus aureus, Bacillus cereus, Corynebacterium species, Acinetobacter baumanii, Enterobacter aerogenes, Pseudomonas aeruginosa,23(57.5%) were post-operative cases in which majority showed Stapylococcus aureus followed by Staphylococcus epidermidis and Pseudomonas aeruginosa,3(7.5%) were endogenous endophthalmitis in which only one case showed Streptococcus mitis.
Keywords
- Michael S, Kresloff, Alessando, Castellarin and Marco. A.Zarbin, Endophthalmitis. Surv Ophthalmol 1998 Nov- Dec;43(3):193-224, doi: 10.1016/s0039-6257(98)00036-8.
- A K KHURANA, Textbook of Comprehensive Ophthalmology, Diseases of Uveal tract; 4th edition p 151.
- Borne MJ, Shields CL, De Porter P, EthyaH. Bilateral viral endophthalmitis is the presenting sign of severe combined immunodeficiency. Arch Ophthalmol 1994 Oct;112(10):1280-1, doi: 10.1001/ archopht.1994.01090220030013.
- Sharma S. Ocular infections: Research in India. Indian J Med Microbiol 2010 Apr-Jun;28(2):91-4 doi: 10.4103/0255-0857.62481.
- Madhavan HN, Anand AR, Lily Therese K, “Infectious endphthalmitis,” Inn journal of microbiology, 17(3)1999:108-115.
- Han DP, Wisniewski SR, Wilson LA, Barza M, Vine AK, Doft BH. Spectrum and susceptibilities of microbiologic isolates in the endopthalmitis vitrectomy study. Am J Ophthalmol. 1996;122(1):1–17
- Lalwani GA, Flynn HW Jr, Scott IU, et al. Acute-onset endophthalmitis after cataract surgery (2000-2004): incidence, clinical settings, and visual acuity outcomes after treatment. Am J Ophthalmol. 2008;145(3):466-72. doi: 10.1016/j.ajo.2007.10.019.
- Durand ML, Dohlman CH. Successful prevention of bacterial endophthalmitis through corneal transplantation. Trans Am Ophthalmol Soc. 1999; 97:317- 324; discussion 324-328.
- Gower EW, Lindsley K, Tulenko SE, et al. Perioperative antibiotics for prevention of acute endophthalmitis after cataract surgery. Cochrane Database Syst Rev. 2017;2(2): CD006364. doi: 10.1002/14651858.CD006364.pub4
- Duan F, Huang J, Wu D, et al. Bacteriological profile of post-traumatic endophthalmitis in southern China. Graefes Arch ClinExp Ophthalmol. 2011;249(10):1527-32. doi: 10.1007/s00417-011-1696-1.
- Kessel L, Flesner P, Andresen J, Erngaard D, Tendal B, Hjortdal J. Antibiotic prevention of post-cataract endophthalmitis: a systematic review and metaanalysis. Acta Ophthalmol. 2015 Jun;93(4):303-17. doi: 10.1111/aos.12627.
- Deramo VA, Lai JC, Fastenberg DM, Udell IJ. Acute endophthalmitis in eyes treated prophylactically with gatifloxacin and moxifloxacin. Am J Ophthalmol. 2006 Nov;142(5):721-5. doi: 10.1016/j.ajo.2006.05.054
Abstract Views: 127
PDF Views: 0