Severe Cholestatic Jaundice in Hyperthyroidism: A Case Report

Introduction: Thyroid storm is an endocrinological emergency caused by an exacerbation of the hyperthyroid state and is characterised by multi organ dysfunction. Liver dysfunction or injury predominantly of a cholestatic type is one of the atypical manifestations of hyperthyroidism and has been previously described in literature. Case report: We report a case of a 47 year old nonalcoholic male patient who presented with jaundice and weight loss due to hyperthyroidism complicated by cholestatic hepatic injury and hyperkalaemia. Conclusion: This case highlights the varied multi organ dysfunctions seen in a patient with hyperthyroidism with emphasis on liver injury mainly to increase awareness among clinicians in resource limited settings. Mechanisms of liver injury due to thyroid storm or hyperthyroidism are discussed in the literature review.