A B C D E F G H I J K L M N O P Q R S T U V W X Y Z All
Chapadia, C.
- Recurrent Episode of Priapism due to Quetiapine in a Bipolar Patient
Authors
1 Griffin Memorial Hospital, Oklahoma, US
2 North Penn Cardiovascular Institute, US
3 Medical College, Baroda, IN
4 Chapadia Medical Center, IN
5 Miller School of Medicine, Miami, US
Source
The Indian Practitioner, Vol 69, No 7 (2016), Pagination: 45-46Abstract
Priapism is a rare side effect of anti-psychotics. Both typical and atypical anti-psychotics can cause priapism. Priapism means persistent and most of the times painful penile erection not associated with sexual stimulation. Priapism can cause urinary retention, cavernosa fibrosis, gangrene and even impotency if it is not treated properly in time. About 50% of priapism patients end up having impotency1. Drugs account for 25-40% of priapism2. The most common drugs causing priapism are anti-hypertensives and anti-psychotics1.
In anti-psychotics, second generation anti-psychotics are more associated with priapism. But the information in the literature is limited. Most common anti-psychotics causing priapism are Risperidone, Olanzapine and Quetiapine. We are reporting a case of recurrent episode of priapism due to Quetiapine use.
Keywords
Priapism, Bipolar Disorder, Anti-Psychotics.
References
- Thompson JW, Jr, Ware MR, Blashfield RK. Psychotropic medication and priapism: a comprehensive review. J Clin Psychiatry. 1990;51(10):430–433
- Penaskovic, Kenan M., Fasiha Haq, and Shakeel Raza. “Priapism During Treatment With Olanzapine, Quetiapine, and Risperidone in a Patient With Schizophrenia: A Case Report.” Primary Care Companion to The Journal of Clinical Psychiatry 12.5 (2010): PCC.09l00939. PMC. Web. 29 Mar. 2016.
- Jackson JC, Torrence CL. Quetiapine-induced Priapism Requiring Frequent Emergency Admissions: A Case Report. Urology Case Reports. 2015;3(1):1-2. doi:10.1016/j.eucr.2014.09.003.
- M.J. Geraci, S.L. McCoy, P.M. Crum, et al. Anti-psychoticinduced priapism in an HIV patient: a cytochrome P450mediated drug interaction Int J Emerg Med, 3 (2010), pp. 81–84.
- Atypical Antipsychotic-Induced Temporomandibular Joint Dislocation
Authors
1 Miller School of Medicine, Miami, US
2 North Shore University, US
3 North Penn cardiovascular Institute, US
4 Medical College, Baroda, IN
5 Chapadia Medical Center, IN
Source
The Indian Practitioner, Vol 69, No 9 (2016), Pagination: 28-29Abstract
Dystonia is a kind of movement disorder that leads to prolonged muscle contractions, leading to abnormal postures of the trunk, neck, face, arms or legs. It can be generalised or focal and primary or secondary depending on the etiology. It can manifest as oculogyric crisis, abnormal tongue movements, torticollis and opisthotonus. Laryngeal and pharyngeal spasms may as well be life threatening. Drug induced dystonia is most commonly caused by the drugs which alter the dopaminergic and cholinergic balance in the nigrostriatum (basal ganglia). Most of these drugs cause dystonia by blocking D2 dopaminergic receptors in the nigrostriatum which leads to an unopposed and unbalanced cholinergic output. Antipsychotics along with metoclopramide are the most common drugs which are responsible for the various dystonias and a common presentation in the psychiatric wards.Keywords
Risperidone, Dystonia, Dislocation.References
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- Singh H, Levinson DF, Simpson GM, et al. Acute dystonia during fixed-dose neuroleptic treatment. J Clin Psychopharmacol. 1990;10(6):389–396. PubMed doi:10.1097/00004714-199010060-00002
- [Zones, 2006; Mendhekar et al. 2009; Das et al. 2008; Jhanjee and Gupta, 2009; Sankhla et al. 1998].
- Levine M, Burns MJ. Antipsychotic agent. In: Shannon MW, Borron SW, Burns MJ, editors. Haddad and Winchester’s Clinical Management of Poisoning and Drug Overdose. 4th ed. Philadelphia, PA: Saunders Elsevier; 2007. p. 703-20.
- Sankhla C, Lai EC, Jankovic J. Peripherally induced oromandibular dystonia. J Neurol Neurosurg Psychiatry 1998;65(5):722-8.