The Indian Practitioner

N. N. Redkar ¹, K. J. Rawat ², V. Agarwal ³, P. Kolhe ³, J. Shah ³

Affiliations
1 Seth G.S. Medical College & K.E.M.H. Parel, Mumbai, IN
2 Seth G.S. Medical College & K.E.M.H. Parel, 11/6, Skyscraper Building, A.L. Nair Road, Mumbai Central - 400008, IN
3 Seth G.S.Medical College & K.E.M.H. Parel, Mumbai, IN

Abstract

Pulmonary alveolar proteinosis (PAP) is a rare, congenital or acquired disease characterised by impaired surfactant clearance that leads to accumulation of an amorphous, lipoproteinaceous material in the alveoli, largely made up of surfactant protein (SP) - A,B,C,D which are Periodic Acid Schiff (PAS) positive. A 53 year old male presented with anorexia, weight loss, progressive dyspnoea on exertion&cough with whitish mucoid expectoration. Investigations showed severe hypoxia and elevated serum LDH. X ray chest had Bat-wing appearance with bilateral infiltration with spared lung apices. HRCT chest showed bilateral alveolar filling with 'crazy-pavement' appearance with well preserved interlobular and alveolar architecture suggestive of PAP. Bronchoscopic aspiration of bronchoalveolar lavage (BAL) fluid examination confirmed the diagnosis of PAP. Patient improved with alveolar aspiration.

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K. J. Rawat ¹, A. Kuwar ¹, A. A. Shivchhand ¹

Affiliations
1 Seth G.S. Medical College & K.E.M.H. Parel, IN

Abstract

No Abstract.

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K. J. Rawat ¹, J. P. Rawat ², S.S. Patil ²

Affiliations
1 KEM Hospital, Parel, Mumbai, IN
2 J R Hospital, Mumbai Central, IN

Abstract

No Abstract.

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